CHRNA4 Produits
(Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
Catégories
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
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Catégories CHRNA4 en vedette
CHRNA4 Anticorps
High quality antibodies with extensive validation data.
CHRNA4 Kits ELISA
Reliable ELISA kits for a wide range of species.
CHRNA4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CHRNA4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (5)
N° du produit
ABIN7444463
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA
Validations
- (4)
N° du produit
ABIN5611309
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (3)
N° du produit
ABIN736746
Quantité
100 μL
Fiche technique
Fiche technique
CHRNA4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN456521
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1144815
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1144816
Quantité
96 tests
Fiche technique
Fiche technique
CHRNA4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349402
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418266
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7418314
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CHRNA4
: "Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors." dans: BMC cancer, Vol. 15, pp. 152, (2015) (PubMed).: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." dans: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
: "Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 7, pp. 935-46, (2006) (PubMed).
: "How mutations in the nAChRs can cause ADNFLE epilepsy." dans: Epilepsia, Vol. 43 Suppl 5, pp. 112-22, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à CHRNA4
neuronal acetylcholine receptor subunit alpha-4 (CpipJ_CPIJ002434), neuronal acetylcholine receptor subunit alpha-4-like (LOC100368057), cholinergic receptor nicotinic alpha 4 subunit (CHRNA4), cholinergic receptor, nicotinic, alpha 4b (chrna4b), cholinergic receptor nicotinic alpha 4 subunit (Chrna4), cholinergic receptor, nicotinic, alpha polypeptide 4 (Chrna4), Acra-4, Acra4, BFNC, EBN, EBN1, ENFL1, NACHR, NACHRA4, NACRA4, NARACProtein level used designations for CHRNA4
- neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor subunit alpha-4-like
- cholinergic receptor, nicotinic, alpha 4
- neuronal acetylcholine receptor subunit alpha-4-like
- neuronal nicotinic acetylcholine receptor alpha 4 subunit
- alpha-4 subunit, nicotinic acetylcholine receptor
- cholinergic receptor, nicotinic, alpha polypeptide 4
- neuronal nicotinic acetylcholine receptor alpha-4 subunit
- Neuronal nicotinic acetylcholine receptor alpha 4 subunit
- cholinergic receptor, nicotinic, alpha 4 subunit
- neuronal acetylcholine receptor alpha-4 subunit
- a4 nicotinic receptor
- acetylcholine receptor alpha 4 neural
- acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit
- alpha4 nAChR
- alpha4-nAChR
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- Chromatin Target of PRMT1
- Chromogranin A
- Chromosome 1 Open Reading Frame 190
- Chromosome 1 Open Reading Frame 27
- Chromosome 1 Open Reading Frame 61
- Chromosome 1 Open Reading Frame 84
- Chromosome 10 Open Reading Frame 116
- Chromosome 11open Reading Frame 9
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