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CIDEA Produits

(Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Catégories

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010].

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Catégories CIDEA en vedette

CIDEA Anticorps

High quality antibodies with extensive validation data.

CIDEA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CIDEA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
  • (4)
N° du produit ABIN514417
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7147273
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (2)
N° du produit ABIN514415
Quantité 100 μL
Fiche technique Fiche technique

CIDEA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6213582
Quantité 96 tests
Fiche technique Fiche technique

CIDEA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1349472
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7421812
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7414642
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CIDEA

Hu, Ru, Zhou, Xiao, Sun, Zhang, Gao, Li, Zhang, Yang: "Lung cancer-derived extracellular vesicles induced myotube atrophy and adipocyte lipolysis via the extracellular IL-6-mediated STAT3 pathway." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 8, pp. 1091-1102, (2019) (PubMed).

Sans, Bonnafous, Rousseau, Patouraux, Canivet, Leclere, Tran-Van-Nhieu, Luci, Bailly-Maitre, Xu, Lee, Minehira, Anty, Tran, Iannelli, Gual: "The Differential Expression of Cide Family Members is Associated with Nafld Progression from Steatosis to Steatohepatitis." dans: Scientific reports, Vol. 9, Issue 1, pp. 7501, (2019) (PubMed).

Rohm, Schäfer, Laurent, Üstünel, Niopek, Algire, Hautzinger, Sijmonsma, Zota, Medrikova, Pellegata, Ryden, Kulyte, Dahlman, Arner, Petrovic, Cannon, Amri, Kemp, Steinberg, Janovska, Kopecky, Wolfrum et al.: "An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice. ..." dans: Nature medicine, Vol. 22, Issue 10, pp. 1120-1130, (2016) (PubMed).

Cavalera, Axling, Berger, Holm: "Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue." dans: Nutrition & metabolism, Vol. 13, pp. 91, (2016) (PubMed).

Wang-Johanning, Rycaj, Plummer, Li, Yin, Frerich, Garza, Shen, Lin, Yan, Glynn, Dorsey, Hunt, Ambs, Johanning: "Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors." dans: Journal of the National Cancer Institute, Vol. 104, Issue 3, pp. 189-210, (2012) (PubMed).

Ito, Nagasawa, Omae, Ide, Akasaka, Murakami: "Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes." dans: Journal of lipid research, Vol. 52, Issue 8, pp. 1450-60, (2011) (PubMed).

Ito, Nagasawa, Hara, Ide, Murakami: "Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes." dans: Journal of lipid research, Vol. 51, Issue 7, pp. 1676-84, (2010) (PubMed).

Puri, Ranjit, Konda, Nicoloro, Straubhaar, Chawla, Chouinard, Lin, Burkart, Corvera, Perugini, Czech: "Cidea is associated with lipid droplets and insulin sensitivity in humans." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 22, pp. 7833-8, (2008) (PubMed).

Kawai, Matsumoto, Takeda, Sanjo, Akira: "ZIP kinase, a novel serine/threonine kinase which mediates apoptosis." dans: Molecular and cellular biology, Vol. 18, Issue 3, pp. 1642-51, (1998) (PubMed).

Synonymes et noms alternatifs relatifs à CIDEA

cell death-inducing DFFA-like effector a (CIDEA), cell death-inducing DNA fragmentation factor, alpha subunit-like effector A (Cidea), cell death-inducing DFFA-like effector a (Cidea), cell death-inducing DFFA-like effector a (cidea), cell death-inducing DFFA-like effector a L homeolog (cidea.L), AW212747, CIDE-A, cide-a, CIDEA, MGC89985

Protein level used designations for CIDEA

  • cell death activator CIDE-A
  • cell death-inducing DFFA-like effector A
  • cell death-inducing DFFA-like effector a
  • cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
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