CLCN3 Produits
(Chloride Channel 3 (CLCN3))
Catégories
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Catégories CLCN3 en vedette
CLCN3 Anticorps
High quality antibodies with extensive validation data.
CLCN3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CLCN3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Application
WB, IHC
Validations
- (1)
- (5)
N° du produit
ABIN2776327
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN6260874
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, ICC, IF
Validations
- (3)
N° du produit
ABIN1027722
Quantité
100 μg
Fiche technique
Fiche technique
CLCN3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1349568
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3113843
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3134382
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CLCN3
: "CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons." dans: Journal of cell science, Vol. 129, Issue 7, pp. 1378-90, (2016) (PubMed).: "Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics." dans: Immunity, inflammation and disease, Vol. 2, Issue 4, pp. 205-13, (2015) (PubMed).
: "Chloride-hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro." dans: Physiological reports, Vol. 3, Issue 11, (2015) (PubMed).
: "Calcium entry via TRPC1 channels activates chloride currents in human glioma cells." dans: Cell calcium, Vol. 53, Issue 3, pp. 187-94, (2013) (PubMed).
: "A quantitative assay for lysosomal acidification rates in human osteoclasts." dans: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).
: "Expression and localization of CLC chloride transport proteins in the avian retina." dans: PLoS ONE, Vol. 6, Issue 3, pp. e17647, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à CLCN3
chloride voltage-gated channel 3 (CLCN3), chloride voltage-gated channel 3 (Clcn3), chloride channel, voltage-sensitive 3 (Clcn3), chloride channel 3 (clcn3), chloride channel protein 3 (PTRG_03131), chloride channel protein 3 (BDBG_05668), chloride channel protein 3 (MCYG_04420), chloride channel, voltage-sensitive 3 (clcn3), chloride channel, voltage-sensitive 3 S homeolog (clcn3.S), ClC-3, clc-3, CLC3, Clc3, clc3, CLCN3, fb78c02, wu:fb78c02Protein level used designations for CLCN3
- H(+)/Cl(-) exchange transporter 3
- chloride channel 3
- chloride channel protein 3
- chloride transporter ClC-3
- protein kinase C-regulated chloride channel
- clC-3
- chloride channel Clc-3
- Chloride channel protein 3
- H(+)/Cl(-) exchange transporter 3-like
- putative chloride channel ClC-3
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