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CLEC4A Produits

(C-Type Lectin Domain Family 4, Member A (CLEC4A))

Catégories

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008].

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Catégories CLEC4A en vedette

CLEC4A Anticorps

High quality antibodies with extensive validation data.

CLEC4A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CLEC4A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (5)
N° du produit ABIN7180295
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
N° du produit ABIN7193222
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
N° du produit ABIN3016507
Quantité 100 μL
Fiche technique Fiche technique

CLEC4A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730459
Quantité 96 tests
Fiche technique Fiche technique

CLEC4A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274354
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274364
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122063
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CLEC4A

Bloem, García-Vallejo, Vuist, Cobb, van Vliet, van Kooyk: "Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells." dans: Frontiers in immunology, Vol. 4, pp. 103, (2013) (PubMed).

Bloem, Vuist, van der Plas, Knippels, Garssen, García-Vallejo, van Vliet, van Kooyk: "Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain." dans: PLoS ONE, Vol. 8, Issue 6, pp. e66266, (2013) (PubMed).

Tel, Sittig, Blom, Cruz, Schreibelt, Figdor, de Vries: "Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 5005-12, (2013) (PubMed).

Tjomsland, Spångeus, Sandström, Borch, Messmer, Larsson: "Semi mature blood dendritic cells exist in patients with ductal pancreatic adenocarcinoma owing to inflammatory factors released from the tumor." dans: PLoS ONE, Vol. 5, Issue 10, pp. e13441, (2010) (PubMed).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." dans: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." dans: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Meyer-Wentrup, Cambi, Joosten, Looman, de Vries, Figdor, Adema: "DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production." dans: Journal of leukocyte biology, Vol. 85, Issue 3, pp. 518-25, (2009) (PubMed).

Meyer-Wentrup, Benitez-Ribas, Tacken, Punt, Figdor, de Vries, Adema: "Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production." dans: Blood, Vol. 111, Issue 8, pp. 4245-53, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à CLEC4A

zinc finger protein 705A (ZNF705A), C-type lectin domain family 4 member A (CLEC4A), C-type lectin domain family 4, member A (Clec4a), C-type lectin domain family 4, member a2 (Clec4a2), CLEC4A, Clec4a, CLECSF6, Clecsf6, DCIR, Dcir1, DDB27, LLIR

Protein level used designations for CLEC4A

  • C-type lectin domain family 4, member A
  • C-type lectin, superfamily member 6
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6
  • C-type lectin DDB27
  • C-type lectin domain family 4 member A
  • C-type lectin superfamily member 6
  • dendritic cell immunoreceptor
  • lectin-like immunoreceptor
  • C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6
  • dendritic cell inhibitory receptor 1
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