COMP Produits
(Cartilage Oligomeric Matrix Protein (COMP))
Catégories
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
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Catégories COMP en vedette
COMP Anticorps
High quality antibodies with extensive validation data.
COMP Kits ELISA
Reliable ELISA kits for a wide range of species.
COMP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
COMP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (5)
N° du produit
ABIN390893
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7433240
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (4)
N° du produit
ABIN6138864
Quantité
100 μL
Fiche technique
Fiche technique
COMP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
N° du produit
ABIN6720567
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6954397
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6954398
Quantité
96 tests
Fiche technique
Fiche technique
COMP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Source
Validations
- (1)
- (1)
N° du produit
ABIN1047991
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505321
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
N° du produit
ABIN7534406
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits COMP
: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." dans: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).: "Joint remodeling outcome of serum levels of Dickkopf-1 (DKK1), cartilage oligomeric matrix protein (COMP), and C-telopeptide of type II collagen (CTXII) in rheumatoid arthritis." dans: Central-European journal of immunology, Vol. 45, Issue 1, pp. 73-79, (2020) (PubMed).
: "Elevated serum cartilage oligomeric matrix protein and the metalloproteinase-ADAMTS7 levels are associated with vascular calcification in maintenance hemodialysis patients." dans: Seminars in dialysis, Vol. 33, Issue 4, pp. 322-329, (2020) (PubMed).
: "Inhibition of cartilage degeneration and subchondral bone deterioration by Spinacia oleracea in human mimic of ACLT-induced osteoarthritis." dans: Food & function, Vol. 11, Issue 9, pp. 8273-8285, (2020) (PubMed).
: "Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate‑induced osteoarthritis rats." dans: Molecular medicine reports, Vol. 16, Issue 4, pp. 3841-3848, (2018) (PubMed).
: "Decreased Plasma COMP and Increased Plasma CTX-II Levels in a Chinese Pseudoachondroplasia Family with Novel COMP Mutation." dans: BioMed research international, Vol. 2017, pp. 5809787, (2018) (PubMed).
: "Spinacia oleracea extract attenuates disease progression and sub-chondral bone changes in monosodium iodoacetate-induced osteoarthritis in rats." dans: BMC complementary and alternative medicine, Vol. 18, Issue 1, pp. 69, (2018) (PubMed).
: "MeCP2 Regulates PTCH1 Expression Through DNA Methylation in Rheumatoid Arthritis." dans: Inflammation, Vol. 40, Issue 5, pp. 1497-1508, (2018) (PubMed).
: "A putative Chondroprotective role for IL-1β and MPO in herbal treatment of experimental osteoarthritis." dans: BMC complementary and alternative medicine, Vol. 17, Issue 1, pp. 495, (2017) (PubMed).
: "Cartilage oligomeric matrix protein and hyaluronic acid are sensitive serum biomarkers for early cartilage lesions in the knee joint." dans: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 21, Issue 2, pp. 146-51, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à COMP
cartilage oligomeric matrix protein (COMP), cartilage oligomeric matrix protein (sce3551), cartilage oligomeric matrix protein (CJA_1292), cartilage oligomeric matrix protein (Comp), COMP, EDM1, EPD1, MED, PSACH, THBS5, TSP5Protein level used designations for COMP
- cartilage oligomeric matrix protein
- TSP5
- cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
- cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
- pseudoachondroplasia (epiphyseal dysplasia 1, multiple)
- thrombospondin-5
- putative cartilage oligomeric matrix protein
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