Complement Factor B Produits
(Complement Factor B (CFB))
Catégories
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008].
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Catégories Complement Factor B en vedette
Complement Factor B Anticorps
High quality antibodies with extensive validation data.
Complement Factor B Kits ELISA
Reliable ELISA kits for a wide range of species.
Complement Factor B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Complement Factor B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (7)
N° du produit
ABIN3015550
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7438322
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7438376
Quantité
100 μL
Fiche technique
Fiche technique
Complement Factor B recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
N° du produit
ABIN6720575
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (4)
N° du produit
ABIN6730898
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
N° du produit
ABIN6720576
Quantité
96 tests
Fiche technique
Fiche technique
Complement Factor B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN5854833
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7092743
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Human Cells
Validations
N° du produit
ABIN1096421
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Complement Factor B
: "Protein Expression Profile in Rat Silicosis Model Reveals Upregulation of PTPN2 and Its Inhibitory Effect on Epithelial-Mesenchymal Transition by Dephosphorylation of STAT3." dans: International journal of molecular sciences, Vol. 21, Issue 4, (2020) (PubMed).: "Identification of susceptibility locus shared by IgA nephropathy and inflammatory bowel disease in a Chinese Han population." dans: Journal of human genetics, Vol. 65, Issue 3, pp. 241-249, (2020) (PubMed).
: "Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability." dans: The American journal of pathology, Vol. 188, Issue 10, pp. 2392-2405, (2018) (PubMed).
: "Viral mimic polyinosine-polycytidylic acid potentiates liver injury in trichloroethylene-sensitized mice - Viral-chemical interaction as a novel mechanism." dans: Ecotoxicology and environmental safety, Vol. 155, pp. 101-108, (2018) (PubMed).
: "Adipose tissue complement factor B promotes adipocyte maturation." dans: Biochemical and biophysical research communications, Vol. 495, Issue 1, pp. 740-748, (2017) (PubMed).
: "Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis." dans: Journal of neuroimmunology, Vol. 295-296, pp. 130-8, (2016) (PubMed).
: "Depression of Complement Regulatory Factors in Rat and Human Renal Grafts Is Associated with the Progress of Acute T-Cell Mediated Rejection." dans: PLoS ONE, Vol. 11, Issue 2, pp. e0148881, (2016) (PubMed).
: "Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. ..." dans: Hepatology (Baltimore, Md.), Vol. 62, Issue 1, pp. 118-28, (2015) (PubMed).
: "Atypical hemolytic uremic syndrome: Korean pediatric series." dans: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 57, Issue 3, pp. 431-8, (2015) (PubMed).
: "Identification and confirmation of differentially expressed fucosylated glycoproteins in the serum of ovarian cancer patients using a lectin array and LC-MS/MS." dans: Journal of proteome research, Vol. 11, Issue 9, pp. 4541-52, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à Complement Factor B
complement factor B (CFB), complement factor B (cfb), complement factor B (bf), complement factor B S homeolog (cfb.S), complement factor B L homeolog (cfb.L), complement factor B (bf/c2), complement factor B (LOC100555981), complement factor B (Cfb), AHUS4, AI195813, AI255840, B, BF, bf, Bf, Bf-1, bf/c2, Bf B, bfb-A, BFD, Brre-Bf, C2, CFAB, CFB, Da1-24, FB, Fb, FBI12, GBG, H2-Bf, LOC397725, PBF2, Sp152, zgc:114032Protein level used designations for Complement Factor B
- B-factor, properdin
- C3 proaccelerator
- C3 proactivator
- C3/C5 convertase
- glycine-rich beta glycoprotein
- glycine-rich beta-glycoprotein
- properdin factor B
- complement component factor B
- complement factor B
- complement component 2
- EC-VMFB
- complement factor Bf-1
- Factor B
- alternative-complement pathway C3/C5 convertase
- complement component 2 (within H-2S)
- histocompatibility 2, complement component factor B
- properdin
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