COPS5 Produits
(COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
Catégories
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008].
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Catégories COPS5 en vedette
COPS5 Anticorps
High quality antibodies with extensive validation data.
COPS5 Kits ELISA
Reliable ELISA kits for a wide range of species.
COPS5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
COPS5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, ChIP
Validations
- (7)
N° du produit
ABIN7266497
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (4)
N° du produit
ABIN3022512
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN6138883
Quantité
100 μL
Fiche technique
Fiche technique
COPS5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381254
Quantité
96 tests
Fiche technique
Fiche technique
COPS5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350059
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2712494
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN7447863
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits COPS5
: "Nedd8 hydrolysis by UCH proteases in Plasmodium parasites." dans: PLoS pathogens, Vol. 15, Issue 10, pp. e1008086, (2019) (PubMed).: "COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain." dans: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9299-309, (2015) (PubMed).
: "Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells." dans: British journal of cancer, Vol. 112, Issue 10, pp. 1687-702, (2015) (PubMed).
: "COPS5 (Jab1) protein increases ? site processing of amyloid precursor protein and amyloid ? peptide generation by stabilizing RanBP9 protein levels." dans: The Journal of biological chemistry, Vol. 288, Issue 37, pp. 26668-77, (2013) (PubMed).
: "The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E577-85, (2011) (PubMed).
: "In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 37, pp. 16331-5, (2010) (PubMed).
: "Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development." dans: Molecular and cellular biology, Vol. 28, Issue 18, pp. 5621-33, (2008) (PubMed).
: "The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis." dans: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 12557-65, (2007) (PubMed).
: "Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif." dans: FEBS letters, Vol. 579, Issue 7, pp. 1693-701, (2005) (PubMed).
: "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase." dans: Nature cell biology, Vol. 6, Issue 12, pp. 1229-35, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à COPS5
COP9 signalosome subunit 5 (CSN5), COP9 signalosome subunit 5 (COPS5), COP9 signalosome subunit 5 (cops5), COP9 signalosome complex subunit 5 (CpipJ_CPIJ012314), COP9 signalosome complex subunit 5 (Bm1_46585), COP9 signalosome complex subunit 5 (VDBG_06932), COP9 signalosome complex subunit 5 (LOAG_01443), COP9 signalosome complex subunit 5 (csn5), COP9 signalosome subunit 5 (Cops5), COP9 signalosome subunit 5 S homeolog (cops5.S), COP9 signalosome complex subunit 5 (csn-5), AI303502, BcDNA.LD14392, BcDNA:LD14392, CG14884, CH5, COPS5, CSN-5, Csn5, csn5, CSN5, DCH5, Dch5, dch5, Dmel\\CG14884, JAB1, Jab1, JAB1/CSN5, jab1/csn5, JadBp, l(3)89Cf, l(3)L4032, l(3)M203, MGC76063, MOV-34, Mov34, quo, Sgn5, SGN5, zgc:73130Protein level used designations for COPS5
- CG14884-PA
- CG14884-PB
- COP9 complex subunit 5
- CSN5-PA
- CSN5-PB
- JUN activation domain-binding protein-1
- Jun activation domain binding protein
- drosophila COP9 signalosome homolog 5
- COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
- COP9 signalosome complex subunit 5
- signalosome subunit 5
- COP9 signalosome subunit 5
- COP9 signalosome complex subunit 5-like
- COP9 complex S5
- Jun activation domain-binding protein 1
- Jun coactivator
- Kip1 C-terminus-interacting protein 2
- COP9 constitutive photomorphogenic-like subunit 5
- c-Jun activation domain binding protein-1
- 38 kDa Mov34 homolog
- COP9 constitutive photomorphogenic homolog subunit 5
- jun activation domain-binding protein 1
- COP9 (constitutive photomorphogenic) homolog, subunit 5
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