CPSF4 Produits
(Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
Catégories
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Catégories CPSF4 en vedette
CPSF4 Anticorps
High quality antibodies with extensive validation data.
CPSF4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CPSF4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7147920
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (fro), IHC (p)
Validations
- (2)
N° du produit
ABIN1386751
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC
Validations
- (2)
N° du produit
ABIN6261007
Quantité
100 μL
Fiche technique
Fiche technique
CPSF4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN1098798
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350238
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2128680
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CPSF4
: "Alanine substitutions within a linker region of the influenza A virus non-structural protein 1 alter its subcellular localization and attenuate virus replication." dans: The Journal of general virology, Vol. 92, Issue Pt 8, pp. 1832-42, (2011) (PubMed).Synonymes et noms alternatifs relatifs à CPSF4
cleavage and polyadenylation specific factor 4 (CPSF4), cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4), cleavage and polyadenylation specific factor 4 (LOC733099), cleavage and polyadenylation specific factor 4 (LOC100360200), cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S), cleavage and polyadenylation specific factor 4 (cpsf4), cleavage and polyadenylation specific factor 4 (Cpsf4), 30kDa, C79664, cpsf30, CPSF30, nar, NAR, neb1, NEB1Protein level used designations for CPSF4
- no arches
- GLEAN_10339
- cleavage and polyadenylation specific factor 4
- cleavage and polyadenylation specificity factor subunit 4
- cleavage and polyadenylation specific factor 4, 30kDa
- CPSF 30 kDa subunit
- cleavage and polyadenylation specific factor 4, 30kD subunit
- cleavage and polyadenylation specificity factor 30 kDa subunit
- clipper homolog
- clipper/CPSF 30K
- musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit
- NS1 effector domain-binding protein 1
- cleavage-polyadenylation specificity factor, 30kD
- neb-1
- no arches homolog
- no arches-like zinc finger protein
- cleavage-polyadenylation specificity factor, 30 kD
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