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CRTC1 Produits

(CREB Regulated Transcription Coactivator 1 (CRTC1))
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons.

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Catégories CRTC1 en vedette

CRTC1 Anticorps

High quality antibodies with extensive validation data.

CRTC1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CRTC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CRTC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Chicken, Human
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (4)
N° du produit ABIN746558
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, FACS, ICC
Validations
  • (4)
N° du produit ABIN6241239
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (3)
  • (3)
N° du produit ABIN969066
Quantité 100 μL
Fiche technique Fiche technique

CRTC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955105
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Sandwich ELISA
Validations
N° du produit ABIN427062
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6203034
Quantité 96 tests
Fiche technique Fiche technique

CRTC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350404
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7420138
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3091973
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CRTC1

Heinrich, Böer, Tzvetkov, Oetjen, Knepel: "Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC." dans: Bioscience reports, Vol. 29, Issue 2, pp. 77-87, (2009) (PubMed).

Fehr, Röser, Belge, Löning, Bullerdiek: "A closer look at Warthin tumors and the t(11;19)." dans: Cancer genetics and cytogenetics, Vol. 180, Issue 2, pp. 135-9, (2008) (PubMed).

Winnes, Mölne, Suurküla, Andrén, Persson, Enlund, Stenman: "Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas." dans: Genes, chromosomes & cancer, Vol. 46, Issue 6, pp. 559-63, (2007) (PubMed).

Tonon, Modi, Wu, Kubo, Coxon, Komiya, ONeil, Stover, El-Naggar, Griffin, Kirsch, Kaye: "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway." dans: Nature genetics, Vol. 33, Issue 2, pp. 208-13, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à CRTC1

CREB regulated transcription coactivator 1 (CRTC1), CREB regulated transcription coactivator 1 (Crtc1), CREB regulated transcription coactivator 1 (crtc1), CREB regulated transcription coactivator 1b (crtc1b), AI413414, CRTC1, crtc1, fc68c05, MECT1, Mect1, mKIAA0616, pde4cb, R74955, si:ch211-255d18.1, si:ch211-255d18.8, TORC-1, TORC1, WAMTP1, wu:fc68c05

Protein level used designations for CRTC1

  • CREB-regulated transcription coactivator 1
  • mucoepidermoid carcinoma translocated protein 1
  • transducer of regulated cAMP response element-binding protein (CREB) 1
  • TORC-1
  • mucoepidermoid carcinoma translocated 1
  • mucoepidermoid carcinoma translocated protein 1 homolog
  • transducer of CREB protein 1
  • transducer of regulated cAMP response element-binding protein 1
  • CREB regulated transcription coactivator 1
  • CREB-regulated transcription coactivator 1-like
  • CH211-255D18.10
  • CH211-255D18.9
  • CREB regulated transcription coactivator 1b
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4C
  • phosphodiesterase 4C, cAMP-specific b
  • zfTorc1
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