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CSTB Produits

(Cystatin B (Stefin B) (CSTB))

Catégories

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008].

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Catégories CSTB en vedette

CSTB Anticorps

High quality antibodies with extensive validation data.

CSTB Kits ELISA

Reliable ELISA kits for a wide range of species.

CSTB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CSTB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, IF, IP
Validations
  • (5)
N° du produit ABIN7148987
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (5)
N° du produit ABIN560509
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
N° du produit ABIN6261072
Quantité 100 μL
Fiche technique Fiche technique

CSTB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
N° du produit ABIN6955179
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6973896
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966192
Quantité 96 tests
Fiche technique Fiche technique

CSTB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350601
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7400477
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7399697
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CSTB

Unić, Derek, Duvnjak, Patrlj, Rakić, Kujundžić, Renjić, Štoković, Dinjar, Jukic, Grgurević: "Diagnostic specificity and sensitivity of PIVKAII, GP3, CSTB, SCCA1 and HGF for the diagnosis of hepatocellular carcinoma in patients with alcoholic liver cirrhosis." dans: Annals of clinical biochemistry, Vol. 55, Issue 3, pp. 355-362, (2019) (PubMed).

Penna, Cerciello, Chambery, Russo, Cernilogar, Pedone, Perrone-Capano, Cappello, Di Giaimo, Crispino: "Cystatin B Involvement in Synapse Physiology of Rodent Brains and Human Cerebral Organoids." dans: Frontiers in molecular neuroscience, Vol. 12, pp. 195, (2019) (PubMed).

Zenón, Segarra, Gonzalez, Meléndez: "Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages." dans: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 5, pp. 703-15, (2014) (PubMed).

Cantres-Rosario, Plaud-Valentín, Gerena, Skolasky, Wojna, Meléndez: "Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders." dans: AIDS, Vol. 27, Issue 3, pp. 347-56, (2013) (PubMed).

Gashenko, Lebedeva, Brak, Tsykalenko, Vinokurova, Korolenko: "Evaluation of serum procathepsin B, cystatin B and cystatin C as possible biomarkers of ovarian cancer." dans: International journal of circumpolar health, Vol. 72, (2013) (PubMed).

Rodriguez-Franco, Cantres-Rosario, Plaud-Valentin, Romeu, Rodríguez, Skolasky, Meléndez, Cadilla, Melendez: "Dysregulation of macrophage-secreted cathepsin B contributes to HIV-1-linked neuronal apoptosis." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36571, (2012) (PubMed).

Eliyahu, Shtraizent, He, Chen, Shalgi, Schuchman: "Identification of cystatin SA as a novel inhibitor of acid ceramidase." dans: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35624-33, (2011) (PubMed).

Bespalova, Adkins, Pranzatelli, Burmeister: "Novel cystatin B mutation and diagnostic PCR assay in an Unverricht-Lundborg progressive myoclonus epilepsy patient." dans: American journal of medical genetics, Vol. 74, Issue 5, pp. 467-71, (1997) (PubMed).

Blaser: "Type B gastritis, aging, and Campylobacter pylori." dans: Archives of internal medicine, Vol. 148, Issue 5, pp. 1021-2, (1988) (PubMed).

Moffat, Ferrier, Karmazyn: "A possible role for endogenous prostaglandins in the electrophysiological effects of acetylstrophanthidin on isolated canine ventricular tissues." dans: Circulation research, Vol. 58, Issue 4, pp. 486-94, (1986) (PubMed).

Synonymes et noms alternatifs relatifs à CSTB

cystatin B (CSTB), cystatin B (stefin B) (CSTB), cystatin B (Cstb), cystatin B (stefin B) (cstb), cystatin 14a, tandem duplicate 2 (cst14a.2), cystatin B (CYSB), cystatin B (cpi1), cystatin-B (LOC101123265), AA960480, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6, ATCYS6, ATCYSB, CPI1, CST6, cst6, CSTB, Cyb, cystatin B, EPM1, Epm1, epm1, EPM1A, LOC100008600, LOC100136235, MGC189005, PME, pme, STFB, Stfb, stfb, ULD

Protein level used designations for CSTB

  • CPI-B
  • cystatin-B
  • liver thiol proteinase inhibitor
  • cystatin B protein
  • stefin-B
  • cystatin B (stefin B)
  • cystatin beta
  • cystatin-beta
  • stefin B
  • stefin C
  • stefin-C
  • cystatin B
  • Leukocyte cysteine proteinase inhibitor 1
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