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CTCFL Produits

(CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].

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Catégories CTCFL en vedette

CTCFL Anticorps

High quality antibodies with extensive validation data.

CTCFL Kits ELISA

Reliable ELISA kits for a wide range of species.

CTCFL Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CTCFL recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7172781
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (6)
  • (1)
N° du produit ABIN129668
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ChIP-seq, ChIP
Validations
  • (2)
N° du produit ABIN6971455
Quantité 100 μL
Fiche technique Fiche technique

CTCFL recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
N° du produit ABIN6965537
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5594143
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6225336
Quantité 96 tests
Fiche technique Fiche technique

CTCFL recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122188
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350632
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3091944
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CTCFL

Janssen, Moscona, Elchebly, Papadakis, Redpath, Wang, Rubin, van Kempen, Spatz: "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." dans: Cell death discovery, Vol. 6, pp. 1, (2020) (PubMed).

Freitas, Malheiros, Stávale, Biassi, Zamunér, de Souza Begnami, Soares, Vettore: "Expression of cancer/testis antigens is correlated with improved survival in glioblastoma." dans: Oncotarget, Vol. 4, Issue 4, pp. 636-46, (2013) (PubMed).

Rosa-Garrido, Ceballos, Alonso-Lecue, Abraira, Delgado, Gandarillas: "A cell cycle role for the epigenetic factor CTCF-L/BORIS." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39371, (2012) (PubMed).

Macaluso, Caracciolo, Rizzo, Sun, Montanari, Russo, Bellipanni, Khalili, Giordano: "Integrating role of T antigen, Rb2/p130, CTCF and BORIS in mediating non-canonical endoplasmic reticulum-dependent death pathways triggered by chronic ER stress in mouse medulloblastoma." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 9, pp. 1841-50, (2012) (PubMed).

Fiorentino, Macaluso, Miranda, Montanari, Russo, Bagella, Giordano: "CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer." dans: Molecular cancer research : MCR, Vol. 9, Issue 2, pp. 225-33, (2011) (PubMed).

Jones, Ogunkolade, Szary, Aarum, Mumin, Patel, Pieri, Sheer: "Widespread expression of BORIS/CTCFL in normal and cancer cells." dans: PLoS ONE, Vol. 6, Issue 7, pp. e22399, (2011) (PubMed).

Bhan, Negi, Shao, Glazer, Chuang, Gaykalova, Sun, Sidransky, Ha, Califano: "BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 13, pp. 4267-76, (2011) (PubMed).

Hines, Bazarov, Mukhopadhyay, Yaswen: "BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas." dans: PLoS ONE, Vol. 5, Issue 3, pp. e9738, (2010) (PubMed).

Monk, Hitchins, Hawes: "Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation development." dans: Molecular human reproduction, Vol. 14, Issue 6, pp. 347-55, (2008) (PubMed).

Dougherty, Ichim, Liu, Reznik, Min, Ghochikyan, Agadjanyan, Reznik: "Selective apoptosis of breast cancer cells by siRNA targeting of BORIS." dans: Biochemical and biophysical research communications, Vol. 370, Issue 1, pp. 109-12, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à CTCFL

CCCTC-binding factor like (CTCFL), CCCTC-binding factor (zinc finger protein)-like (Ctcfl), CCCTC-binding factor like (Ctcfl), BORIS, Boris, CT27, CTCF-T, CTCFL, dJ579F20.2, HMGB1L1, OTTMUSG00000016680

Protein level used designations for CTCFL

  • BORIS-like protein
  • CTCF paralog
  • CTCF-like protein
  • HMG-1L1
  • brother of the regulator of imprinted sites
  • cancer/testis antigen 27
  • putative high mobility group protein 1-like 1
  • putative high mobility group protein B1-like 1
  • transcriptional repressor CTCFL
  • zinc finger protein CTCF-T
  • CCCTC-binding factor (zinc finger protein)-like
  • CCCTC-binding factor-like protein
  • BORIS
  • Brother of the regulator of imprinted sites
  • likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL)
  • brother of regulator of imprinted sites
  • transcriptional repressor CTCFL-like
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