Cullin 4B Produits
(Cullin 4B (CUL4B))
Catégories
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories Cullin 4B en vedette
Cullin 4B Anticorps
High quality antibodies with extensive validation data.
Cullin 4B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Cullin 4B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (6)
N° du produit
ABIN3187726
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN6139255
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Mouse
Application
WB, IHC, IHC (p)
Validations
- (6)
N° du produit
ABIN1490724
Quantité
100 μL
Fiche technique
Fiche technique
Cullin 4B recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6215470
Quantité
96 tests
Fiche technique
Fiche technique
Cullin 4B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350769
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3091967
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3130673
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Cullin 4B
: "Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." dans: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).: "Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks." dans: Human molecular genetics, Vol. 19, Issue 7, pp. 1324-34, (2010) (PubMed).
: "Cullins in human intra-uterine growth restriction: expressional and epigenetic alterations." dans: Placenta, Vol. 31, Issue 2, pp. 151-7, (2010) (PubMed).
: "A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndrome." dans: Clinical genetics, Vol. 77, Issue 2, pp. 141-4, (2010) (PubMed).
: "CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation." dans: Molecular cell, Vol. 40, Issue 1, pp. 9-21, (2010) (PubMed).
: "Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, ..." dans: American journal of human genetics, Vol. 80, Issue 2, pp. 345-52, (2007) (PubMed).
: "Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation." dans: American journal of human genetics, Vol. 80, Issue 3, pp. 561-6, (2007) (PubMed).
: "Dioxin receptor is a ligand-dependent E3 ubiquitin ligase." dans: Nature, Vol. 446, Issue 7135, pp. 562-6, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à Cullin 4B
cullin 4B (CUL4B), cullin 4B (Cul4b), cullin 4B (cul4b), cullin 4B S homeolog (cul4b.S), cullin 4B (Tb927.3.1290), 2700050M05Rik, AA409770, CUL-4B, im:7140950, im:7150765, MGC115611, mKIAA0695, MRXHF2, mrxhf2, MRXS15, MRXSC, mrxsc, RGD1564494, SFM2, sfm2, Tb03.1J15.620Protein level used designations for Cullin 4B
- CUL-4B
- cullin-4B
- cullin 4B
- cullin-4B-like
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