CYB5R3 Produits
(Cytochrome B5 Reductase 3 (CYB5R3))
Catégories
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010].
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Catégories CYB5R3 en vedette
CYB5R3 Anticorps
High quality antibodies with extensive validation data.
CYB5R3 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYB5R3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYB5R3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
N° du produit
ABIN560603
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7160982
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN514976
Quantité
50 μg
Fiche technique
Fiche technique
CYB5R3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966213
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966212
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN813300
Quantité
96 tests
Fiche technique
Fiche technique
CYB5R3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1350883
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122569
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350885
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYB5R3
: "Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase." dans: Mutation research, Vol. 852, pp. 503162, (2020) (PubMed).: "Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine." dans: Toxicology and applied pharmacology, Vol. 366, pp. 64-74, (2019) (PubMed).
: "Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice." dans: Archives of toxicology, Vol. 92, Issue 4, pp. 1625-1638, (2019) (PubMed).
: "The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice." dans: PloS one, Vol. 9, Issue 8, pp. e105371, (2014) (PubMed).
: "Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme." dans: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 34796-802, (2006) (PubMed).
: "RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1." dans: Journal of cell science, Vol. 118, Issue Pt 12, pp. 2661-70, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à CYB5R3
cytochrome b5 reductase 3 (CYB5R3), cytochrome b5 reductase 3 (Cyb5r3), cytochrome b5 reductase 3 (cyb5r3), cytochrome b5 reductase 3 L homeolog (cyb5r3.L), NADH-cytochrome b5 reductase (CNM00240), NADH-cytochrome b5 reductase (Tb11.47.0018), NADH-cytochrome b5 reductase (cyb5r1), 0610016L08Rik, 2500002N19Rik, B5R, C85115, CB5R, DDBDRAFT_0218707, DDBDRAFT_0266821, DDB_0218707, DDB_0266821, Dia-1, DIA1, Dia1, dia1, fc32h03, Nadhcb5, RNNADHCB5, WU:AL591952.1-001, WU:AL591952.1-002, WU:AL591952.1-003, WU:Cyb5r3, wu:fc32h03, zgc:77071Protein level used designations for CYB5R3
- NADH-cytochrome b5 reductase 3
- NADH-cytochrome b5 reductase 3 membrane-bound form
- NADH-cytochrome b5 reductase 3 soluble form
- diaphorase-1
- B5R
- Diaphorase (NADH) (cytochrome b-5 reductase)
- diaphorase 1
- diaphorase 1 (NADH)
- NADH-cytochrome b5 reductase
- cytochrome b5 reductase 3
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