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Cyclin A1 Produits

(Cyclin A1 (CCNA1))
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories Cyclin A1 en vedette

Cyclin A1 Anticorps

High quality antibodies with extensive validation data.

Cyclin A1 Kits ELISA

Reliable ELISA kits for a wide range of species.

Cyclin A1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Cyclin A1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7180926
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6261140
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat, Sheep
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
  • (2)
N° du produit ABIN714026
Quantité 100 μL
Fiche technique Fiche technique

Cyclin A1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955144
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN4993357
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN4993356
Quantité 96 tests
Fiche technique Fiche technique

Cyclin A1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122517
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348428
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7424668
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Cyclin A1

Abdel-Hamid, Zakaria, Nawaya, Eldomany, El-Shishtawy: "Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma." dans: Recent patents on anti-cancer drug discovery, Vol. 18, Issue 2, pp. 187-199, (2023) (PubMed).

Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." dans: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).

Yuan, Xi, Chen, Zhu, Kang, Zou, Wang, Bu: "STAT3 stimulates adipogenic stem cell proliferation and cooperates with HMGA2 during the early stage of differentiation to promote adipogenesis." dans: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1360-1366, (2017) (PubMed).

Zeng, Ma, Chen, Qiu, Wu, Ling, Zeng: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." dans: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).

Ghate, Das, Chaudhuri, Panja, Mandal: "Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio." dans: Cell death discovery, Vol. 2, pp. 15062, (2016) (PubMed).

Yuan, Zheng, Li, Xiang, Gao, Ran, Sun, Huang, Xie, Du, Xiao: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." dans: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, (2016) (PubMed).

Wang, Wang: "Studying the relationship between cell cycle and Alzheimer's disease by gold nanoparticle probes." dans: Analytical biochemistry, Vol. 489, pp. 32-7, (2015) (PubMed).

Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: "An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7." dans: PLoS ONE, Vol. 8, Issue 12, pp. e82293, (2013) (PubMed).

Ochsenreither, Majeti, Schmitt, Stirewalt, Keilholz, Loeb, Wood, Choi, Bleakley, Warren, Hudecek, Akatsuka, Weissman, Greenberg: "Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen." dans: Blood, Vol. 119, Issue 23, pp. 5492-501, (2012) (PubMed).

Yang, Morosetti, Koeffler: "Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines." dans: Cancer research, Vol. 57, Issue 5, pp. 913-20, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à Cyclin A1

cyclin A1 (CCNA1), cyclin A1 (ccna1), cyclin A1 L homeolog (ccna1.L), CYCLIN A1;2 (CYCA1;2), cyclin A1 (Ccna1), cyclin A1 S homeolog (ccna1.S), CCNA1, ccna1, cyclin-A1, Cyclin-A1, cyclin-A1-2, fd14f08, MGC81965, MGC132235, wu:fd14f08, wu:fi20d12, zgc:111869

Protein level used designations for Cyclin A1

  • cyclin-A1
  • cyclin A1
  • cyclin-A1-like
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