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Cyclin-Dependent Kinase 9 Produits

(Cyclin-Dependent Kinase 9 (CDK9))
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008].

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Catégories Cyclin-Dependent Kinase 9 en vedette

Cyclin-Dependent Kinase 9 Anticorps

High quality antibodies with extensive validation data.

Cyclin-Dependent Kinase 9 Kits ELISA

Reliable ELISA kits for a wide range of species.

Cyclin-Dependent Kinase 9 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Cyclin-Dependent Kinase 9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, IF, ChIP-seq
Validations
  • (7)
N° du produit ABIN7266597
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (4)
N° du produit ABIN969042
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (5)
N° du produit ABIN3015519
Quantité 100 μL
Fiche technique Fiche technique

Cyclin-Dependent Kinase 9 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1114469
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1114470
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method Quantitative
Validations
N° du produit ABIN778482
Quantité 96 tests
Fiche technique Fiche technique

Cyclin-Dependent Kinase 9 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1776650
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348986
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7416046
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Cyclin-Dependent Kinase 9

Sayed, Yang, He, Pfleger, Abdellatif: "Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription." dans: Circulation. Heart failure, Vol. 8, Issue 1, pp. 138-48, (2015) (PubMed).

Moldovan, Moran: "The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition." dans: PLoS genetics, Vol. 11, Issue 5, pp. e1005121, (2015) (PubMed).

Ma, Chen, Wright, Pillai, Chellappan, Cress: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." dans: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).

Montanuy, Torremocha, Hernández-Munain, Suñé: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." dans: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).

Sabò, Lusic, Cereseto, Giacca: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." dans: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).

Zhou, Lu, Park, Wilson-Chiru, Linton, Brady: "Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription." dans: Journal of virology, Vol. 80, Issue 10, pp. 4781-91, (2006) (PubMed).

Jang, Mochizuki, Zhou, Jeong, Brady, Ozato: "The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription." dans: Molecular cell, Vol. 19, Issue 4, pp. 523-34, (2005) (PubMed).

Liu, Herrmann: "Differential localization and expression of the Cdk9 42k and 55k isoforms." dans: Journal of cellular physiology, Vol. 203, Issue 1, pp. 251-60, (2005) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Fu, Peng, Lee, Price, Flores: "Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription." dans: The Journal of biological chemistry, Vol. 274, Issue 49, pp. 34527-30, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à Cyclin-Dependent Kinase 9

cyclin dependent kinase 9 (CDK9), cyclin-dependent kinase 9 (CDC2-related kinase) (cdk9), cyclin-dependent kinase 9 L homeolog (cdk9.L), cyclin-dependent kinase 9 (Cdk9), Cyclin-dependent kinase 9 (Cdk9), cyclin-dependent kinase 9 (cdk9), cyclin-dependent kinase 9 (CDC2-related kinase) (Cdk9), cyclin dependent kinase 9 (Cdk9), cyclin-dependent kinase 9 S homeolog (cdk9.S), C-2k, c-2k, CDC2L4, cdc2l4, cdk9, CDK9, CG5179, CTK1, ctk1, Dmel\\CG5179, P-TEF, P-TEFb, PITALRE, pitalre, PTefb, TAK, tak, wu:fb22e09, wu:fc06c02

Protein level used designations for Cyclin-Dependent Kinase 9

  • CDC2-related kinase
  • cell division cycle 2-like protein kinase 4
  • cell division protein kinase 9
  • serine/threonine protein kinase PITALRE
  • serine/threonine-protein kinase PITALRE
  • tat-associated kinase complex catalytic subunit
  • cyclin-dependent kinase 9 (CDC2-related kinase)
  • cell division protein kinase 9-B
  • cyclin-dependent kinase 9-B
  • CG5179-PA
  • Cdk9-PA
  • Cyclin-dependent kinase9 2.7
  • p43 PITALRE
  • positive transcription elongation factor b
  • positive transcription elongation factor b, small subunit
  • cyclin-dependent kinase 9
  • cell division protein kinase 9-A
  • cyclin-dependent kinase 9-A
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