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CYP11A1 Produits

(Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))

Catégories

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008].

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Catégories CYP11A1 en vedette

CYP11A1 Anticorps

High quality antibodies with extensive validation data.

CYP11A1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CYP11A1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CYP11A1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cow, Human, Mouse, Rat
Application WB, IF (p), IHC (p), FACS, IF (cc), IHC (fro)
Validations
  • (5)
  • (5)
N° du produit ABIN701530
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (9)
N° du produit ABIN1512804
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN6744438
Quantité 100 μL
Fiche technique Fiche technique

CYP11A1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966228
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966229
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955234
Quantité 96 tests
Fiche technique Fiche technique

CYP11A1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350925
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350923
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7407913
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CYP11A1

Sagaradze, Basalova, Kirpatovsky, Ohobotov, Grigorieva, Balabanyan, Kamalov, Efimenko: "Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." dans: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).

Ommati, Heidari, Jamshidzadeh, Zamiri, Sun, Sabouri, Wang, Ahmadi, Javanmard, Seifi, Mousapour, Yeganeh: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." dans: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).

Lin, Liu, Guo, Liu, Mi, Zhang: "Promotion of the prehierarchical follicle growth by postovulatory follicles involving PGE2 -EP2 signaling in chickens." dans: Journal of cellular physiology, Vol. 233, Issue 11, pp. 8984-8995, (2018) (PubMed).

Medwid, Guan, Yang: "Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring." dans: Environmental toxicology and pharmacology, Vol. 43, pp. 203-8, (2016) (PubMed).

Mahata, Zhang, Kolodziejczyk, Proserpio, Haim-Vilmovsky, Taylor, Hebenstreit, Dingler, Moignard, Göttgens, Arlt, McKenzie, Teichmann: "Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis." dans: Cell reports, Vol. 7, Issue 4, pp. 1130-42, (2014) (PubMed).

LaVoie, Whitfield, Shi, King, Bose, Hui: "STARD6 is expressed in steroidogenic cells of the ovary and can enhance de novo steroidogenesis." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 4, pp. 430-5, (2014) (PubMed).

Jia, Domenico, Takeda, Han, Wang, Armstrong, Reisdorph, OConnor, Lucas, Gelfand: "Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 20, pp. 8152-7, (2013) (PubMed).

Hu, Dong, Chen, Lu, Han, Qiu, Chen, Qin, Li, Gu, Xia, Sun, Li, Wang: "Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells." dans: Reproductive biology and endocrinology : RB&E, Vol. 11, pp. 72, (2013) (PubMed).

He, Xu, Chen, Liu, Xi: "Abnormal apoptosis of trophoblastic cells is related to the up-regulation of CYP11A gene in placenta of preeclampsia patients." dans: PLoS ONE, Vol. 8, Issue 3, pp. e59609, (2013) (PubMed).

Arboleda, Lee, Parnaik, Fleming, Banerjee, Ferraz-de-Souza, Délot, Rodriguez-Fernandez, Braslavsky, Bergadá, DellAngelica, Nelson, Martinez-Agosto, Achermann, Vilain: "Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome." dans: Nature genetics, Vol. 44, Issue 7, pp. 788-92, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à CYP11A1

cytochrome P450 family 11 subfamily A member 1 (CYP11A1), cholesterol side-chain cleavage enzyme, mitochondrial-like (LOC101827747), cytochrome P450 cholesterol side-chain cleavage (CYP11A1), cytochrome P450, family 11, subfamily a, polypeptide 1 (Cyp11a1), cytochrome P450, family 11, subfamily A, polypeptide 1 (CYP11A1), cscc, CYP11A, Cyp11a, CYP11A1, CYPXIA1, Cypxia1, D9Ertd411e, P450(scc), P450SCC, P450scc, Scc, SSC

Protein level used designations for CYP11A1

  • cholesterol side-chain cleavage enzyme, mitochondrial
  • cytochrome P450 11A1
  • cytochrome P-450 cholesterol side-chain cleavage enzyme
  • Cholesterol desmolase
  • Cytochrome P450 11A1
  • Cytochrome P450(scc)
  • cholesterol desmolase
  • cytochrome P450(scc)
  • cholesterol 20-22 desmolase
  • cholesterol monooxygenase (side-chain cleaving)
  • cytochrome P450, subfamily XIA (cholesterol side chain cleavage)
  • cytochrome P450C11A1
  • steroid 20-22-lyase
  • cholesterol side chain cleavage
  • cytochrome P450 side-chain cleavage enzyme
  • cytochrome P450, 11a, cholesterol side-chain cleavage
  • P450(scc)
  • cholesterol side-chain cleavage cytochrome P450
  • cytochrome P450 11a cholesterol side chain cleavage
  • cytochrome P450 subfamily 11A
  • Cholesterol side-chain cleavage enzyme, mitochondrial
  • CYPXIA1
  • cytochrome P450scc
  • cytochrome P450 family 11 subfamily A polypeptide 1
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