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CYP11B1 Produits

(Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Catégories

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008].

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Catégories CYP11B1 en vedette

CYP11B1 Anticorps

High quality antibodies with extensive validation data.

CYP11B1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CYP11B1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CYP11B1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7435544
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN750823
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN6746765
Quantité 100 μL
Fiche technique Fiche technique

CYP11B1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966230
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955235
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955236
Quantité 96 tests
Fiche technique Fiche technique

CYP11B1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350927
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7407919
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7407916
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CYP11B1

Tyczewska, Rucinski, Ziolkowska, Trejter, Szyszka, Malendowicz: "Expression of selected genes involved in steroidogenesis in the course of enucleation-induced rat adrenal regeneration." dans: International journal of molecular medicine, Vol. 33, Issue 3, pp. 613-23, (2014) (PubMed).

Strushkevich, Gilep, Shen, Arrowsmith, Edwards, Usanov, Park: "Structural insights into aldosterone synthase substrate specificity and targeted inhibition." dans: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 315-24, (2013) (PubMed).

Miyata, Kudo, Lee, Yang, Gelboin, Fernandez-Salguero, Kimura, Gonzalez: "Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene." dans: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 23963-8, (1999) (PubMed).

Zhu, von Dippe, Xing, Levy: "Membrane topology and cell surface targeting of microsomal epoxide hydrolase. Evidence for multiple topological orientations." dans: The Journal of biological chemistry, Vol. 274, Issue 39, pp. 27898-904, (1999) (PubMed).

Hassett, Aicher, Sidhu, Omiecinski: "Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants." dans: Human molecular genetics, Vol. 3, Issue 3, pp. 421-8, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1 (CYP11B1), cytochrome P450 family 11 subfamily B member 1 (CYP11B1), cytochrome P450, family 11, subfamily b, polypeptide 1 (Cyp11b1), cytochrome P450, subfamily XI B, polypeptide 1 (CYP11B1), AA389061, Cp11ba, CPN1, CYP11B, Cyp11b, Cyp11b-1, FHI, P450C11, P450c11, RATCP11BA

Protein level used designations for CYP11B1

  • cytochrome P450 11B1, mitochondrial
  • CYPXIB1
  • cytochrome P-450c11
  • cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1
  • cytochrome P450C11
  • cytochrome p450 XIB1
  • steroid 11-beta-hydroxylase
  • steroid 11-beta-monooxygenase
  • steroid-11-beta-hydroxylase
  • Cytochrome P450, subfamily XIB, polypeptide 1 (steroid 11-beta-hydroxylase)
  • P450(11 beta)-DS
  • P450C11
  • aldosterone synthase
  • cytochrome P450(11 beta)-DS
  • cytochrome P450, subfamily 11B, polypeptide 1
  • 11-beta-hydroxylase
  • 11beta-hydroxylase
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