CYP11B2 Produits
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Catégories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].
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Catégories CYP11B2 en vedette
CYP11B2 Anticorps
High quality antibodies with extensive validation data.
CYP11B2 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP11B2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP11B2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN1679468
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN655163
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (3)
N° du produit
ABIN7257862
Quantité
200 μL
Fiche technique
Fiche technique
CYP11B2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955237
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955238
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Sandwich ELISA
Validations
N° du produit
ABIN424543
Quantité
96 tests
Fiche technique
Fiche technique
CYP11B2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7392893
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Yeast
Validations
N° du produit
ABIN5623843
Quantité
500 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN5623846
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP11B2
: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." dans: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).: "[Differences in adrenal steroid hormones production in pubertal rats exposed to low doses of endocrine disruptor DDT during prenatal and postnatal development]." dans: Biomeditsinskaia khimiia, Vol. 63, Issue 4, pp. 306-311, (2018) (PubMed).
: "Regulation of CYP11B1 and CYP11B2 steroidogenic genes by hypoxia-inducible miR-10b in H295R cells." dans: Marine pollution bulletin, Vol. 85, Issue 2, pp. 344-51, (2014) (PubMed).
: "Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism." dans: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 2, pp. E257-62, (2014) (PubMed).
: "Structural insights into aldosterone synthase substrate specificity and targeted inhibition." dans: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 315-24, (2013) (PubMed).
: "The renin-angiotensin-aldosterone system in cerebral small vessel disease." dans: Journal of neurology, Vol. 255, Issue 7, pp. 993-1000, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à CYP11B2
cytochrome P450 family 11 subfamily B member 2 (CYP11B2), cytochrome P450, family 11, subfamily b, polypeptide 2 (Cyp11b2), aldosterone synthase (Cyp11b2), cytochrome P450, family 11, subfamily B, polypeptide 2 (CYP11B2), cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 (CYP11B2), ALDOS, Cp45as, CPN2, Cpn2, CYP11B, Cyp11b, Cyp11b-2, Cyp11b3, CYP11BL, CYPXIB2, P-450C18, P450aldo, P450C18, RNCP45ASProtein level used designations for CYP11B2
- aldosterone synthase
- aldosterone-synthesizing enzyme
- cytochrome P-450Aldo
- cytochrome P-450C18
- cytochrome P450 11B2, mitochondrial
- cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2
- mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2
- steroid 11-beta-monooxygenase
- steroid 11-beta/18-hydroxylase
- steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo
- CYPXIB2
- cytochrome P450C11
- steroid 11-beta-hydroxylase
- steroid-11-beta-hydroxylase
- CYPXIB3
- Cytochrome P450 subfamily XIB polypeptide 2 (aldosterone synthase)
- Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase)
- P450-Aldo-1
- P450-Aldo-2
- cytochrome P450 11B3, mitochondrial
- cytochrome P450, subfamily 11B, polypeptide 2
- cytochrome P450-Aldo-1
- cytochrome P450-Aldo-2
- mitochondrial cytochrome P450 11B2
- cytochrome P450, family 11, subfamily B, polypeptide 2
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