CYP1A2 Produits
(Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
Catégories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008].
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Catégories CYP1A2 en vedette
CYP1A2 Anticorps
High quality antibodies with extensive validation data.
CYP1A2 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP1A2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP1A2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (6)
N° du produit
ABIN1497712
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (2)
- (3)
N° du produit
ABIN655272
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN947768
Quantité
100 μg
Fiche technique
Fiche technique
CYP1A2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6955229
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6955230
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6955231
Quantité
96 tests
Fiche technique
Fiche technique
CYP1A2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1350938
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350937
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7397363
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP1A2
: "Liver lobe and strain differences in the activity of murine cytochrome P450 enzymes." dans: Toxicology, Vol. 404-405, pp. 76-85, (2019) (PubMed).: "Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 160, Issue 1, pp. 173-179, (2018) (PubMed).
: "Reduction of Aflatoxin B1 Toxicity by Lactobacillus plantarum C88: A Potential Probiotic Strain Isolated from Chinese Traditional Fermented Food "Tofu"." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0170109, (2017) (PubMed).
: "Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates." dans: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 47, Issue 11, pp. 951-961, (2017) (PubMed).
: "Phenethyl isothiocyanate and indole-3-carbinol from cruciferous vegetables, but not furanocoumarins from apiaceous vegetables, reduced PhIP-induced DNA adducts in Wistar rats." dans: Molecular nutrition & food research, Vol. 60, Issue 9, pp. 1956-66, (2016) (PubMed).
: "Apiaceous vegetable consumption decreases PhIP-induced DNA adducts and increases methylated PhIP metabolites in the urine metabolome in rats." dans: The Journal of nutrition, Vol. 145, Issue 3, pp. 442-51, (2015) (PubMed).
: "Differential expression of HO-1 and CYP1A2 during up-regulation of ERK in stressed fish hepatocytes." dans: Environmental monitoring and assessment, Vol. 187, Issue 1, pp. 4147, (2014) (PubMed).
: "Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 107-15, (2014) (PubMed).
: "Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 12, pp. 1982-90, (2014) (PubMed).
: "Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. ..." dans: Human molecular genetics, Vol. 20, Issue 10, pp. 2071-7, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à CYP1A2
cytochrome P450 family 1 subfamily A member 2 (CYP1A2), cytochrome P450 1A2 (CYP1A2), cytochrome P450 LM4 (LOC100328937), cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2), cytochrome P450 1A2 (VDBG_06455), cytochrome P450 1A2-like (LOC101825565), cytochrome P450 1A2 (LOC102130662), CP12, CP450, CYP-IA2, Cyp1a1, CYP1A2, CYP1A5, CYPD45, CYPIA2, P-450d, P3-450, P450(PA), P450-3, P450-PM4, RATCYPD45Protein level used designations for CYP1A2
- CYPIA2
- P450 form 4
- aryl hydrocarbon hydroxylase
- cytochrome P(3)450
- cytochrome P450 1A2
- cytochrome P450 4
- cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2
- cytochrome P450-P3
- dioxin-inducible P3-450
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
- P450 LM4
- P450 isozyme 4
- cytochrome P450 isozyme 4
- cytochrome P450-PM4
- aromatic compound inducible
- cytochrome P450 family 1 subfamily a polypeptide 1
- cytochrome P450, 1a2, aromatic compound inducible
- cytochrome P450-P2
- Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d)
- P-448
- P450-D
- cytochrome P-448
- cytochrome P-450d
- cytochrome P450, 1a2
- cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d)
- cytochrome P450-D
- CYPIA5
- cytochrome P450 1A5
- cytochrome P450 TCDDAA
- Cytochrome P450-MC4
- Hepatic cytochrome P-450MC1
- cytochrome P-450 form 4
- cytochrome P-450IA2
- pulmonary cytochrome P-450MC1
- Cholesterol 25-hydroxylase
- cholesterol 25-hydroxylase
- cytochrome P-450
- cytochrome P450, family 1, subfamily A, polypeptide 2
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