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CYP24A1 Produits

(Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories CYP24A1 en vedette

CYP24A1 Anticorps

High quality antibodies with extensive validation data.

CYP24A1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CYP24A1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CYP24A1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
N° du produit ABIN750838
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
N° du produit ABIN514852
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN1679472
Quantité 100 μg
Fiche technique Fiche technique

CYP24A1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966244
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966245
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955253
Quantité 96 tests
Fiche technique Fiche technique

CYP24A1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350944
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397561
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7406554
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CYP24A1

Smolders, Schuurman, van Strien, Melief, Hendrickx, Hol, van Eden, Luchetti, Huitinga: "Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue." dans: Journal of neuropathology and experimental neurology, Vol. 72, Issue 2, pp. 91-105, (2013) (PubMed).

Kotani, Tanabe, Mizukami, Amagaya, Inoue: "A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers." dans: Biological & pharmaceutical bulletin, Vol. 35, Issue 1, pp. 1-9, (2012) (PubMed).

Helvig, Cuerrier, Hosfield, Ireland, Kharebov, Kim, Ramjit, Ryder, Tabash, Herzenberg, Epps, Petkovich: "Dysregulation of renal vitamin D metabolism in the uremic rat." dans: Kidney international, Vol. 78, Issue 5, pp. 463-72, (2010) (PubMed).

Shen, Bielak, Ferguson, Streeten, Yerges-Armstrong, Liu, Post, OConnell, Hixson, Kardia, Sun, Jhun, Wang, Mehta, Li, Koller, Hakonarson, Keating, Rader, Shuldiner, Peyser, Reilly, Mitchell: "Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 12, pp. 2648-54, (2010) (PubMed).

Peng, Jhaveri, Hussain-Hakimjee, Mehta: "Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1alpha-hydroxyvitamin D5." dans: Carcinogenesis, Vol. 28, Issue 5, pp. 1000-7, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à CYP24A1

cytochrome P450 family 24 subfamily A member 1 (CYP24A1), cytochrome P450, family 24, subfamily a, polypeptide 1 (Cyp24a1), cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1), 24-OHase, 25-hydroxyvitaminD324-hydroxylase, CP24, CP450CC24, CYP24, Cyp24, HCAI, P450-CC24, VITD12

Protein level used designations for CYP24A1

  • 1,25-@dihydroxyvitamin D3 24-hydroxylase
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • 24-OHase
  • cytochrome P450 24A1
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
  • cytochrome P450-CC24
  • exo-mitochondrial protein
  • vitamin D 24-hydroxylase
  • vitamin D(3) 24-hydroxylase
  • 25-hydroxyvitamin D-24-hydroxylase
  • cytochrome P450, 24
  • cytochrome P450, 24a1
  • 24R-Ohase
  • 25-hydroxyvitamin D3 24-hydroxylase
  • Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase)
  • P450-CC24
  • cytochrome P450, subfamily 24
  • 25-hydroxyvitamin D3-24-hydroxylase
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