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CYP26B1 Produits

(Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Catégories

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Catégories CYP26B1 en vedette

CYP26B1 Anticorps

High quality antibodies with extensive validation data.

CYP26B1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CYP26B1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (5)
N° du produit ABIN185731
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN527926
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN392528
Quantité 400 μL
Fiche technique Fiche technique

CYP26B1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6214669
Quantité 96 tests
Fiche technique Fiche technique

CYP26B1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350948
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350946
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7415386
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CYP26B1

Foti, Isoherranen, Zelter, Dickmann, Buttrick, Diaz, Douguet: "Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1." dans: The Journal of pharmacology and experimental therapeutics, Vol. 357, Issue 2, pp. 281-92, (2016) (PubMed).

Chen, Lee, Hsu, Chen, Wang, Chen, Wang, Huang, Huang: "Expression of a splice variant of CYP26B1 in betel quid-related oral cancer." dans: TheScientificWorldJournal, Vol. 2014, pp. 810561, (2014) (PubMed).

Elmabsout, Kumawat, Saenz-Méndez, Krivospitskaya, Sävenstrand, Olofsson, Eriksson, Strid, Valen, Törmä, Sirsjö: "Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cells." dans: PLoS ONE, Vol. 7, Issue 5, pp. e36839, (2012) (PubMed).

Topletz, Thatcher, Zelter, Lutz, Tay, Nelson, Isoherranen: "Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases." dans: Biochemical pharmacology, Vol. 83, Issue 1, pp. 149-63, (2011) (PubMed).

Chen, Lee, Chen, Shieh, Ho, Wang, Lee, Yang, Chen, Chiang, Ko: "CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma." dans: Oral oncology, Vol. 47, Issue 7, pp. 594-600, (2011) (PubMed).

Tay, Dickmann, Dixit, Isoherranen: "A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation." dans: Molecular pharmacology, Vol. 77, Issue 2, pp. 218-27, (2010) (PubMed).

Pavez Loriè, Li, Vahlquist, Törmä: "The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes." dans: Biochimica et biophysica acta, Vol. 1791, Issue 3, pp. 220-8, (2009) (PubMed).

Bowles, Knight, Smith, Wilhelm, Richman, Mamiya, Yashiro, Chawengsaksophak, Wilson, Rossant, Hamada, Koopman: "Retinoid signaling determines germ cell fate in mice." dans: Science (New York, N.Y.), Vol. 312, Issue 5773, pp. 596-600, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à CYP26B1

cytochrome P450 26B1 (CpipJ_CPIJ002537), cytochrome P450 family 26 subfamily B member 1 L homeolog (cyp26b1.L), cytochrome P450 family 26 subfamily B member 1 (CYP26B1), cytochrome P450 family 26 subfamily B member 1 (cyp26b1), cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), cytochrome P450, family 26, subfamily b, polypeptide 1 (cyp26b1), CP26, cyp26a2, CYP26A2, cyp26b1, fc21d03, p450rai-2, P450RAI-2, P450RAI2, RHFCA, wu:fc21d03, wu:fc26h10, zgc:76999

Protein level used designations for CYP26B1

  • cytochrome P450 26B1
  • cytochrome P450, family 26, subfamily B, polypeptide 1
  • cytochrome P450 retinoic acid-inactivating 2
  • cytochrome P450 retinoid metabolizing protein
  • cytochrome P450, subfamily XXVIB, polypeptide 1
  • retinoic acid-metabolizing cytochrome
  • cytochrome P450, 26, retinoic acid B1
  • cytochrome P450RAI-2
  • retinoic acid B1
  • retinoic acid hydroxylase
  • dol
  • stocksteif
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