CYP2C8 Produits
(Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
Catégories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
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Catégories CYP2C8 en vedette
CYP2C8 Anticorps
High quality antibodies with extensive validation data.
CYP2C8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP2C8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (2)
N° du produit
ABIN514832
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (2)
N° du produit
ABIN947772
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, WB, IHC
Validations
- (2)
N° du produit
ABIN6258063
Quantité
100 μL
Fiche technique
Fiche technique
CYP2C8 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6214689
Quantité
96 tests
Fiche technique
Fiche technique
CYP2C8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122581
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350971
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3078039
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP2C8
: "Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8." dans: Frontiers in pharmacology, Vol. 6, pp. 261, (2015) (PubMed).: "Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity." dans: The pharmacogenomics journal, Vol. 11, Issue 2, pp. 121-9, (2011) (PubMed).
: "Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)." dans: American journal of physiology. Renal physiology, Vol. 301, Issue 3, pp. F672-81, (2011) (PubMed).
: "Cytochromes P450: a success story." dans: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à CYP2C8
cytochrome P450 family 2 subfamily C member 8 (CYP2C8), Cytochrome P450 2C8 (CTN_0597), cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8), cytochrome P450 family 2 subfamily C member 8 S homeolog (cyp2c8.1.S), cytochrome P450 family 2 subfamily C member 8 (cyp2c8.1), CPC8, cpc8, cyp2c8, CYP2C74, CYPIIC8, cypiic8, MP-12/MP-20, mp-12/mp-20Protein level used designations for CYP2C8
- P450 form 1
- cytochrome P450 2C8
- cytochrome P450 IIC2
- cytochrome P450 MP-12
- cytochrome P450 MP-20
- cytochrome P450 form 1
- cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- s-mephenytoin 4-hydroxylase
- xenobiotic monooxygenase
- Cytochrome P450 2C8
- cytochrome P450 CYP2C74
- cytochrome P450, family 2, subfamily C, polypeptide 8
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