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CYP2C9 Produits

(Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008].

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Catégories CYP2C9 en vedette

CYP2C9 Anticorps

High quality antibodies with extensive validation data.

CYP2C9 Kits ELISA

Reliable ELISA kits for a wide range of species.

CYP2C9 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CYP2C9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN681208
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN1882233
Quantité 0.1 mL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN392364
Quantité 400 μL
Fiche technique Fiche technique

CYP2C9 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966238
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955247
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955246
Quantité 96 tests
Fiche technique Fiche technique

CYP2C9 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350972
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409971
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3078089
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CYP2C9

Zhang, Lou, Zhang, Zhang, Wang, Xu, Niu, Wang, Wu, Cui: "Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation." dans: Oncotarget, Vol. 8, Issue 9, pp. 15377-15392, (2017) (PubMed).

Strick-Marchand, Dusséaux, Darche, Huntington, Legrand, Masse-Ranson, Corcuff, Ahodantin, Weijer, Spits, Kremsdorf, Di Santo: "A novel mouse model for stable engraftment of a human immune system and human hepatocytes." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0119820, (2015) (PubMed).

Yang, Cui, Hasi, Jia, Gong, Su: "Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China." dans: Genetics and molecular research : GMR, Vol. 9, Issue 3, pp. 1844-51, (2010) (PubMed).

Ikejiri, Wada, Sakamoto, Ito, Nishioka, Nakatani, Tsuji, Yamada, Nakamura, Ito, Nobori: "The association of protein S Tokushima-K196E with a risk of deep vein thrombosis." dans: International journal of hematology, Vol. 92, Issue 2, pp. 302-5, (2010) (PubMed).

Schelleman, Brensinger, Chen, Finkelman, Rieder, Kimmel: "New genetic variant that might improve warfarin dose prediction in African Americans." dans: British journal of clinical pharmacology, Vol. 70, Issue 3, pp. 393-9, (2010) (PubMed).

Ng, Imaoka, Hiroi, Osada, Niwa, Kamataki, Funae: "Production of inhibitory polyclonal antibodies against cytochrome P450s." dans: Drug metabolism and pharmacokinetics, Vol. 18, Issue 3, pp. 163-72, (2004) (PubMed).

Werck-Reichhart, Feyereisen: "Cytochromes P450: a success story." dans: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à CYP2C9

cytochrome P450 family 2 subfamily C member 9 (CYP2C9), CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9

Protein level used designations for CYP2C9

  • cytochrome P-450 S-mephenytoin 4-hydroxylase
  • cytochrome P-450MP
  • cytochrome P450 2C9
  • cytochrome P450 PB-1
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
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