CYP2D6 Produits
(Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
Catégories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories CYP2D6 en vedette
CYP2D6 Anticorps
High quality antibodies with extensive validation data.
CYP2D6 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP2D6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP2D6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7437350
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
N° du produit
ABIN5518823
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IF
Validations
- (3)
N° du produit
ABIN6258047
Quantité
100 μL
Fiche technique
Fiche technique
CYP2D6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966241
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955249
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955248
Quantité
96 tests
Fiche technique
Fiche technique
CYP2D6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350974
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7407760
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7401203
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP2D6
: "Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 470219, (2015) (PubMed).: "Production of inhibitory polyclonal antibodies against cytochrome P450s." dans: Drug metabolism and pharmacokinetics, Vol. 18, Issue 3, pp. 163-72, (2004) (PubMed).
: "Cytochromes P450: a success story." dans: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à CYP2D6
cytochrome P450 family 2 subfamily D member 6 (CYP2D6), cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6), cytochrome 2D6 (CYP2D6), cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b), cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S), cytochrome P450 family 2 subfamily D member 6 (cyp2d6), cytochrome P450 2D6 (CYP2D6), cytochrome P450 2D6-like (LOC100988273), CPD6, CYP2D, cyp2d2, CYP2D6, cyp2d6-a, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2D42, CYP2DL1, CYPIID6, MGC64445, P450-DB1, P450C2D, P450DB1Protein level used designations for CYP2D6
- cytochrome P450 2D6
- cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2
- cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2
- cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6
- cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1
- cytochrome P450-DB1
- debrisoquine 4-hydroxylase
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
- CYPIID6
- cytochrome P450 CYP2D42
- cytochrome P450, family 2, subfamily D, polypeptide 6
- cytochrome P450 2D6-like
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