CYP3A7 Produits
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))
Catégories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. This gene undergoes readthrough transcription with the downstream CYP3AP1 pseudogene, resulting in an isoform with a novel C-terminus, as represented in GeneID:100861540. [provided by RefSeq, Feb 2012].
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Catégories CYP3A7 en vedette
CYP3A7 Anticorps
High quality antibodies with extensive validation data.
CYP3A7 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP3A7 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP3A7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7427744
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN7149266
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN307113
Quantité
200 μg
Fiche technique
Fiche technique
CYP3A7 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955261
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648181
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5653517
Quantité
96 tests
Fiche technique
Fiche technique
CYP3A7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350996
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7401020
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3078308
Quantité
250 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP3A7
: "Ontogeny of CYP3A and P-glycoprotein in the liver and the small intestine of the Göttingen minipig: an immunohistochemical evaluation." dans: Basic & clinical pharmacology & toxicology, Vol. 114, Issue 5, pp. 387-94, (2014) (PubMed).: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).
: "Variability of CYP3A7 expression in human fetal liver." dans: The Journal of pharmacology and experimental therapeutics, Vol. 314, Issue 2, pp. 626-35, (2005) (PubMed).
: "Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells." dans: Drug metabolism and pharmacokinetics, Vol. 17, Issue 1, pp. 42-6, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7 (CYP3A7), cytochrome P450 family 3 subfamily A member 7 (CYP3A7), CP37, CYPIIIA7, P450-HFLAProtein level used designations for CYP3A7
- cytochrome P450 3A7
- aryl hydrocarbon hydroxylase
- cytochrome P450, subfamily IIIA, polypeptide 7
- cytochrome P450-HFLA
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
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