CYP46A1 Produits
(Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
Catégories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008].
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Catégories CYP46A1 en vedette
CYP46A1 Anticorps
High quality antibodies with extensive validation data.
CYP46A1 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP46A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP46A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (3)
N° du produit
ABIN524256
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rat
Application
WB
Validations
- (3)
N° du produit
ABIN2773829
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
N° du produit
ABIN708941
Quantité
100 μL
Fiche technique
Fiche technique
CYP46A1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6955263
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5653518
Quantité
96 tests
Fiche technique
Fiche technique
CYP46A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351000
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3119551
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3120164
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP46A1
: "24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure." dans: Scientific reports, Vol. 6, pp. 33886, (2016) (PubMed).: "Cytochrome P450s and cholesterol homeostasis." dans: Pharmacology & therapeutics, Vol. 112, Issue 3, pp. 761-73, (2006) (PubMed).
: "Differential expression of cholesterol hydroxylases in Alzheimer's disease." dans: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34674-81, (2004) (PubMed).
: "Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain." dans: Biochemistry, Vol. 42, Issue 48, pp. 14284-92, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à CYP46A1
cytochrome P450 family 46 subfamily A member 1 (CYP46A1), cytochrome P450 family 46 subfamily A member 1 L homeolog (cyp46a1.L), cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 (cyp46a1.1), cytochrome P450, family 46 (cyp46a1), cytochrome P450 46A1 (PTRG_08343), cytochrome P450 46A1 (PTRG_09667), cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1), cholesterol 24-hydroxylase (Sgly_1093), cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1), CP46, CYP46, Cyp46, CYP46A1, MGC147389, zgc:109896Protein level used designations for CYP46A1
- CH24H
- cholesterol 24-hydroxylase
- cytochrome P450 46A1
- cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
- cytochrome P450, family 46, subfamily A, polypeptide 1
- cytochrome P450, family 46
- cholestrol 24-hydroxylase
- cytochrome P450, 46 (cholesterol 24-hydroxylase)
- cytochrome P450, 46a1 (cholesterol 24-hydroxylase)
- cholesterol-24S-hydroxylase
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