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DAD1 Produits

(Defender Against Cell Death 1 (DAD1))
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008].

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Catégories DAD1 en vedette

DAD1 Anticorps

High quality antibodies with extensive validation data.

DAD1 Kits ELISA

Reliable ELISA kits for a wide range of species.

DAD1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DAD1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7150599
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN1537513
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA
Validations
  • (1)
N° du produit ABIN514863
Quantité 50 μg
Fiche technique Fiche technique

DAD1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1130573
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1130575
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1130570
Quantité 96 tests
Fiche technique Fiche technique

DAD1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351076
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN1608031
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DAD1

Espinoza, Scarpato, Damiani, Managò, Mereu, Contestabile, Peruzzo, Carninci, Santoro, Papaleo, Mingozzi, Ronzitti, Zucchelli, Gustincich: "SINEUP Non-coding RNA Targeting GDNF Rescues Motor Deficits and Neurodegeneration in a Mouse Model of Parkinson's Disease." dans: Molecular therapy : the journal of the American Society of Gene Therapy, (2019) (PubMed).

Li, Moore, Vasilieva, Sui, Wong, Berne, Somasundaran, Sullivan, Luzuriaga, Greenough, Choe, Farzan: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus." dans: Nature, Vol. 426, Issue 6965, pp. 450-4, (2003) (PubMed).

Crackower, Sarao, Oudit, Yagil, Kozieradzki, Scanga, Oliveira-dos-Santos, da Costa, Zhang, Pei, Scholey, Ferrario, Manoukian, Chappell, Backx, Yagil, Penninger: "Angiotensin-converting enzyme 2 is an essential regulator of heart function." dans: Nature, Vol. 417, Issue 6891, pp. 822-8, (2002) (PubMed).

Pagano: "Vascular gp91(phox): beyond the endothelium." dans: Circulation research, Vol. 87, Issue 1, pp. 1-3, (2000) (PubMed).

Tipnis, Hooper, Hyde, Karran, Christie, Turner: "A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase." dans: The Journal of biological chemistry, Vol. 275, Issue 43, pp. 33238-43, (2000) (PubMed).

Sanjay, Fu, Kreibich: "DAD1 is required for the function and the structural integrity of the oligosaccharyltransferase complex." dans: The Journal of biological chemistry, Vol. 273, Issue 40, pp. 26094-9, (1998) (PubMed).

Kelleher, Gilmore: "DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 10, pp. 4994-9, (1997) (PubMed).

Steller: "Mechanisms and genes of cellular suicide." dans: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1445-9, (1995) (PubMed).

Nakashima, Sekiguchi, Kuraoka, Fukushima, Shibata, Komiyama, Nishimoto: "Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells." dans: Molecular and cellular biology, Vol. 13, Issue 10, pp. 6367-74, (1993) (PubMed).

Synonymes et noms alternatifs relatifs à DAD1

dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (LOC100115214), defender against cell death 1 (DAD1), defender against cell death 1 (dad1), defender against cell death 1 (CC1G_00458), defender against cell death 1 (CpipJ_CPIJ003512), hypothetical protein (PGTG_09898), defender against cell death 1 (Dad1), defender against cell death 1 S homeolog (dad1.S), Defender against death (DAD family) protein (ATDAD1), false DAD1 (fdad1), Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 (dad-1), AI323713, DAD-1, dad1, DAD1, DEFENDER AGAINST APOPTOTIC DEATH 1, F3C3.14, F3C3_14, NV18456, ost2, OST2, si:ch211-9d9.5

Protein level used designations for DAD1

  • dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
  • DAD-1
  • oligosaccharyl transferase subunit DAD1
  • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
  • defender against cell death 1
  • oligosaccharyltransferase 2 homolog
  • oligosaccharyltransferase subunit 2 (non-catalytic)
  • defender against death (DAD1)
  • apoptotic suppressor
  • defender against cell death 1 protein
  • defender against death protein 1
  • defender against apoptotic cell death
  • dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1
  • oligosaccharyl transferase subunit dad1
  • Oligosaccharyl transferase subunit DAD1
  • false DAD1
  • CL0_-2
  • gpm673
  • QCJ15g11
  • CL0_-2_ov
  • p-QCJ15g11
  • AY109816_IDP
  • gnp_QCJ15g11
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