DAXX Produits
(Death-Domain Associated Protein (DAXX))
Catégories
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008].
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Catégories DAXX en vedette
DAXX Anticorps
High quality antibodies with extensive validation data.
DAXX Kits ELISA
Reliable ELISA kits for a wide range of species.
DAXX Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DAXX recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (5)
N° du produit
ABIN514879
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ICC
Validations
- (1)
- (3)
N° du produit
ABIN94302
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (4)
N° du produit
ABIN969493
Quantité
100 μL
Fiche technique
Fiche technique
DAXX recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966275
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966276
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380165
Quantité
2 x 96 tests
Fiche technique
Fiche technique
DAXX recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351120
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351122
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7424761
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DAXX
: "Necrostatin-1 protects hippocampal neurons against ischemia/reperfusion injury via the RIP3/DAXX signaling pathway in rats." dans: Neuroscience letters, Vol. 651, pp. 207-215, (2017) (PubMed).: "Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours." dans: Endocrine-related cancer, Vol. 22, Issue 3, pp. L13-8, (2015) (PubMed).
: "Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas." dans: Nature communications, Vol. 6, pp. 6140, (2015) (PubMed).
: "ATRX represses alternative lengthening of telomeres." dans: Oncotarget, Vol. 6, Issue 18, pp. 16543-58, (2015) (PubMed).
: "TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast." dans: British journal of cancer, Vol. 113, Issue 8, pp. 1244-8, (2015) (PubMed).
: "Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors." dans: Hormones & cancer, Vol. 4, Issue 3, pp. 165-75, (2013) (PubMed).
: "Sp100 provides intrinsic immunity against human papillomavirus infection." dans: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).
: "Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. ..." dans: Nature, Vol. 482, Issue 7384, pp. 226-31, (2012) (PubMed).
: "Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 25, Issue 7, pp. 1033-9, (2012) (PubMed).
: "Altered telomeres in tumors with ATRX and DAXX mutations. ..." dans: Science (New York, N.Y.), Vol. 333, Issue 6041, pp. 425, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à DAXX
death domain associated protein (DAXX), Fas death domain-associated protein (Daxx), 28S ribosomal protein S29, mitochondrial (LOC100226911), death-domain associated protein (Daxx), death domain associated protein (Daxx), death-associated protein 6 L homeolog (daxx.L), death-domain associated protein (daxx), BING2, DAP6, daxx, EAP1, LOC100226911, si:dz179b20.7, wu:fd15c03Protein level used designations for DAXX
- CENP-C binding protein
- ETS1-associated protein 1
- Fas-binding protein
- death domain-associated protein 6
- death-associated protein 6
- fas death domain-associated protein
- death-domain associated protein
- death associated protein 3
- Fas death domain-associated protein
- LOW QUALITY PROTEIN: death domain-associated protein 6
- death-associated protein 6 L homeolog
- fas-binding
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