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DAZL Produits

(Deleted in Azoospermia-Like (DAZL))
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Catégories DAZL en vedette

DAZL Anticorps

High quality antibodies with extensive validation data.

DAZL Kits ELISA

Reliable ELISA kits for a wide range of species.

DAZL Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DAZL recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6139416
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN185441
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7149640
Quantité 100 μg
Fiche technique Fiche technique

DAZL recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1129363
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1129364
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1129362
Quantité 96 tests
Fiche technique Fiche technique

DAZL recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1777509
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3078670
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3123297
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DAZL

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Fang, Angulo, Xia, Sukhwani, Wang, Carey, Mazurie, Cui, Wilkinson, Wiedenheft, Irie, Surani, Orwig, Reijo Pera: "A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells." dans: Nature cell biology, Vol. 20, Issue 6, pp. 655-665, (2018) (PubMed).

Levi, Stemmer, Stein, Shalgi, Ben-Aharon: "Treosulfan induces distinctive gonadal toxicity compared with busulfan." dans: Oncotarget, Vol. 9, Issue 27, pp. 19317-19327, (2018) (PubMed).

Liu, Cai, Jin, Peng, Pan, Zhang, Han, Xu, Lin: "Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance." dans: Cell discovery, Vol. 4, pp. 54, (2018) (PubMed).

Guo, Li, Wang, He, Zheng: "Germ stem cells are active in postnatal mouse ovary under physiological conditions." dans: Molecular human reproduction, Vol. 22, Issue 5, pp. 316-28, (2016) (PubMed).

Levi, Tzabari, Savion, Stemmer, Shalgi, Ben-Aharon: "Dexrazoxane exacerbates doxorubicin-induced testicular toxicity." dans: Reproduction (Cambridge, England), Vol. 150, Issue 4, pp. 357-66, (2015) (PubMed).

Dominguez, Chiang, Sukhwani, Orwig, Reijo Pera: "Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies." dans: Scientific reports, Vol. 4, pp. 6432, (2014) (PubMed).

Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: "The human testis-specific proteome defined by transcriptomics and antibody-based profiling." dans: Molecular human reproduction, Vol. 20, Issue 6, pp. 476-88, (2014) (PubMed).

Harkey, Asano, Zoulas, Torok-Storb, Nagashima, Travis: "Isolation, genetic manipulation, and transplantation of canine spermatogonial stem cells: progress toward transgenesis through the male germ-line." dans: Reproduction (Cambridge, England), Vol. 146, Issue 1, pp. 75-90, (2013) (PubMed).

Barrios, Filipponi, Pellegrini, Paronetto, Di Siena, Geremia, Rossi, De Felici, Jannini, Dolci: "Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells." dans: Journal of cell science, Vol. 123, Issue Pt 6, pp. 871-80, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à DAZL

deleted in azoospermia like (DAZL), deleted in azoospermia-like (DAZL), deleted in azoospermia-like (dazl), deleted in azoospermia-like (Dazl), deleted in azoospermia-like L homeolog (dazl.L), deleted in azoospermia like (dazl), deleted in azoospermia like (Dazl), Daz-like, DAZH, dazh, Dazh, DAZL, dazl-a, dazl-B, DAZL1, dazl1, Dazl1, DAZLA, dazla, Dazla, SPGYLA, spgyla, Tpx-2, Tpx2, Xdazl

Protein level used designations for DAZL

  • DAZ homolog
  • DAZ-like autosomal
  • SPGY-like-autosomal
  • deleted in azoospermia-like 1
  • germline specific RNA binding protein
  • spermatogenesis gene on the Y-like autosomal
  • deleted in azoospermia-like
  • DAZ-like protein
  • deleted in azoospermia-like protein
  • deleted in azoospermia protein 3
  • xtdazl
  • DAZ-like protein A
  • DAZ-like protein B
  • Deleted in azoospermia-like-B
  • deleted in azoospermia-like-A
  • xDazl-A
  • xDazl-B
  • Deleted in azoospermia-like 1
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