DCK Produits
(Deoxycytidine Kinase (DCK))
Catégories
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].
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Catégories DCK en vedette
DCK Anticorps
High quality antibodies with extensive validation data.
DCK Kits ELISA
Reliable ELISA kits for a wide range of species.
DCK Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DCK recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IF, IP, IHC (p), ICC
Validations
- (6)
N° du produit
ABIN2856517
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP, IHC (p), ICC
Validations
- (8)
N° du produit
ABIN2855484
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (7)
N° du produit
ABIN1497773
Quantité
100 μL
Fiche technique
Fiche technique
DCK recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966319
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955345
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5593143
Quantité
96 tests
Fiche technique
Fiche technique
DCK recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351190
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351188
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667827
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DCK
: "Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity." dans: BMC cancer, Vol. 18, Issue 1, pp. 466, (2018) (PubMed).: "Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer." dans: Acta oncologica (Stockholm, Sweden), Vol. 55, Issue 3, pp. 286-96, (2016) (PubMed).
: "The effects of forodesine in murine and human multiple myeloma cells." dans: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).
: "Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity." dans: Blood, Vol. 113, Issue 10, pp. 2145-53, (2009) (PubMed).
: "The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase." dans: Cancer research, Vol. 69, Issue 11, pp. 4567-72, (2009) (PubMed).
: "Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 7, pp. 773-84, (2008) (PubMed).
: "Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants." dans: The Journal of pharmacology and experimental therapeutics, Vol. 323, Issue 3, pp. 935-45, (2007) (PubMed).
: "Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells." dans: Molecular and cellular biochemistry, Vol. 231, Issue 1-2, pp. 173-7, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à DCK
deoxycytidine kinase (DCK), deoxycytidine kinase (dck), deoxycytidine kinase, gene 2 L homeolog (dck.2.L), deoxycytidine kinase, gene 2 (dck.2), deoxycytidine kinase (Dck), Deoxycytidine kinase (FPV059), Deoxycytidine kinase (FPV151), deoxycytidine kinase, gene 1 L homeolog (dck.1.L), dck, DCK, dck1, wu:fc15f06, zgc:101771Protein level used designations for DCK
- deoxynucleoside kinase
- Deoxycytidine kinase
- deoxycytidine kinase
- deoxycytidine kinase 1
- deoxyribonucleoside kinase
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