DCLK2 Produits
(Doublecortin-Like Kinase 2 (DCLK2))
Catégories
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Sep 2010].
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Catégories DCLK2 en vedette
DCLK2 Anticorps
High quality antibodies with extensive validation data.
DCLK2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DCLK2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (3)
N° du produit
ABIN6258107
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
N° du produit
ABIN1881253
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, ICC
Validations
- (2)
N° du produit
ABIN2856229
Quantité
100 μL
Fiche technique
Fiche technique
DCLK2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648188
Quantité
96 tests
Fiche technique
Fiche technique
DCLK2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5508892
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7421590
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7423801
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DCLK2
: "The doublecortin gene family and disorders of neuronal structure." dans: Central nervous system agents in medicinal chemistry, Vol. 10, Issue 1, pp. 32-46, (2010) (PubMed).: "Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 16, pp. 6766-71, (2009) (PubMed).
: "Gene trapping: an antibody-dependent approach for verifying integration in your favorite gene." dans: Cellular & molecular biology letters, Vol. 13, Issue 4, pp. 614-20, (2008) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à DCLK2
doublecortin like kinase 2 (DCLK2), doublecortin-like kinase 2 (Dclk2), doublecortin-like kinase 2a (dclk2a), 6330415M09Rik, AU044875, cb572, CL2, CLICK-II, Click-II, CLICK2, CLIK2, DCAMKL2, Dcamkl2, DCDC3, DCDC3B, DCK2, Dck2, dclk, DCLK2, RGD1308384, sb:cb572, si:dkey-180n16.1Protein level used designations for DCLK2
- CaMK-like CREB regulatory kinase 2
- doublecortin and CaM kinase-like 2
- doublecortin domain-containing protein 3B
- doublecortin-like and CAM kinase-like 2
- serine/threonine-protein kinase DCLK2
- caMK-like CREB regulatory kinase 2
- doublecortin-like kinase 2
- zDCLK
- doublecortin kinase 2
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