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DCLRE1C Produits

(DNA Cross-Link Repair 1C (DCLRE1C))

Catégories

This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity\; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq, Jul 2008].

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Catégories DCLRE1C en vedette

DCLRE1C Anticorps

High quality antibodies with extensive validation data.

DCLRE1C Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DCLRE1C recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6261238
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN653693
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN129558
Quantité 100 μg
Fiche technique Fiche technique

DCLRE1C recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6212692
Quantité 96 tests
Fiche technique Fiche technique

DCLRE1C recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351199
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351198
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3092074
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DCLRE1C

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." dans: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Davies, Pettijohn, Fike, Wang, Nahas, Tunuguntla, Hu, Gatti, McCurdy: "Defective DNA double-strand break repair in pediatric systemic lupus erythematosus." dans: Arthritis and rheumatism, Vol. 64, Issue 2, pp. 568-78, (2012) (PubMed).

Pannicke, Ma, Hopfner, Niewolik, Lieber, Schwarz: "Functional and biochemical dissection of the structure-specific nuclease ARTEMIS." dans: The EMBO journal, Vol. 23, Issue 9, pp. 1987-97, (2004) (PubMed).

Poinsignon, de Chasseval, Soubeyrand, Moshous, Fischer, Haché, de Villartay: "Phosphorylation of Artemis following irradiation-induced DNA damage." dans: European journal of immunology, Vol. 34, Issue 11, pp. 3146-55, (2004) (PubMed).

Poinsignon, Moshous, Callebaut, de Chasseval, Villey, de Villartay: "The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination." dans: The Journal of experimental medicine, Vol. 199, Issue 3, pp. 315-21, (2004) (PubMed).

Ma, Lu, Tippin, Goodman, Shimazaki, Koiwai, Hsieh, Schwarz, Lieber: "A biochemically defined system for mammalian nonhomologous DNA end joining." dans: Molecular cell, Vol. 16, Issue 5, pp. 701-13, (2004) (PubMed).

Ma, Pannicke, Schwarz, Lieber: "Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination." dans: Cell, Vol. 108, Issue 6, pp. 781-94, (2002) (PubMed).

Callebaut, Moshous, Mornon, de Villartay: "Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family." dans: Nucleic acids research, Vol. 30, Issue 16, pp. 3592-601, (2002) (PubMed).

Moshous, Callebaut, de Chasseval, Corneo, Cavazzana-Calvo, Le Deist, Tezcan, Sanal, Bertrand, Philippe, Fischer, de Villartay: "Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency." dans: Cell, Vol. 105, Issue 2, pp. 177-86, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à DCLRE1C

DNA cross-link repair 1C (DCLRE1C), DNA cross-link repair 1C (Dclre1c), 9930121L06Rik, A-SCID, AI661365, Art, artemis, DCLREC1C, hSNM1C, nuclease, RS-SCID, SCIDA, SNM1C, Snm1l

Protein level used designations for DCLRE1C

  • DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
  • artemis protein
  • protein artemis
  • DNA cross-link repair 1C
  • protein artemis-like
  • DNA cross-link repair 1C protein
  • PSO2 homolog
  • SNM1 homolog C
  • SNM1-like protein
  • severe combined immunodeficiency, type a (Athabascan)
  • chSNM1C
  • Artemis protein
  • DNA cross-link repair 1A, PSO2 homolog
  • artemis
  • mArt
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