DcR1 Produits
(Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
Catégories
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008].
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Catégories DcR1 en vedette
DcR1 Anticorps
High quality antibodies with extensive validation data.
DcR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
DcR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DcR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
FACS
Validations
- (3)
N° du produit
ABIN301991
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN6265636
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS
Validations
- (2)
N° du produit
ABIN6579816
Quantité
0.1 mg
Fiche technique
Fiche technique
DcR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960280
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN625360
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5510573
Quantité
96 tests
Fiche technique
Fiche technique
DcR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275773
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1323146
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Human Cells
Validations
N° du produit
ABIN7319098
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DcR1
: "Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells." dans: PLoS ONE, Vol. 14, Issue 4, pp. e0214847, (2019) (PubMed).: "Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells." dans: BMC cancer, Vol. 19, Issue 1, pp. 496, (2019) (PubMed).
: "TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells." dans: Frontiers in immunology, Vol. 10, pp. 2044, (2019) (PubMed).
: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." dans: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).
: "TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis." dans: Scientific reports, Vol. 7, Issue 1, pp. 5514, (2017) (PubMed).
: "Targeting Apoptotic Activity Against Prostate Cancer Stem Cells." dans: International journal of molecular sciences, Vol. 18, Issue 8, (2017) (PubMed).
: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." dans: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma." dans: Stem cells translational medicine, Vol. 3, Issue 2, pp. 172-82, (2014) (PubMed).
: "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes." dans: The Journal of biological chemistry, Vol. 289, Issue 23, pp. 16576-87, (2014) (PubMed).
: "TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells." dans: Anticancer research, Vol. 34, Issue 2, pp. 729-34, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à DcR1
TNF receptor superfamily member 10c (TNFRSF10C), CD263, DCR1, DCR1-TNFR, LIT, TNFRSF10C, TRAIL-R3, TRAILR3, TRIDProtein level used designations for DcR1
- TNF-related apoptosis-inducing ligand receptor 3
- antagonist decoy receptor for TRAIL/Apo-2L
- cytotoxic TRAIL receptor-3
- decoy TRAIL receptor without death domain
- decoy receptor 1
- lymphocyte inhibitor of TRAIL
- tumor necrosis factor receptor superfamily member 10C
- tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
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