DDR1 Produits
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Catégories
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Catégories DDR1 en vedette
DDR1 Anticorps
High quality antibodies with extensive validation data.
DDR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
DDR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DDR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Rat
Application
WB, IHC (p), FACS
Validations
- (5)
N° du produit
ABIN392014
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS, IF
Validations
- (5)
N° du produit
ABIN391458
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF
Validations
- (7)
N° du produit
ABIN3030734
Quantité
0.4 mL
Fiche technique
Fiche technique
DDR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN5526734
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN5526735
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966389
Quantité
96 tests
Fiche technique
Fiche technique
DDR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7274460
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7274462
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351296
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DDR1
: "Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma." dans: Molecular oncology, (2019) (PubMed).: "Normal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implications." dans: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13565-74, (2014) (PubMed).
: "Activated hair follicle stem cells and Wnt/?-catenin signaling involve in pathnogenesis of sebaceous neoplasms." dans: International journal of medical sciences, Vol. 11, Issue 10, pp. 1022-8, (2014) (PubMed).
: "A unique and potent protein binding nature of liposome containing polyethylenimine and polyethylene glycol: a nondisplaceable property." dans: Biotechnology and bioengineering, Vol. 108, Issue 6, pp. 1318-27, (2011) (PubMed).
: "Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis." dans: BMC cancer, Vol. 7, pp. 55, (2007) (PubMed).
: "Sensing extracellular matrix: an update on discoidin domain receptor function." dans: Cellular signalling, Vol. 18, Issue 8, pp. 1108-16, (2006) (PubMed).
: "Professional practice solutions.... How does a healthcare organization deal with conflicting directives between HCFA regulations and Joint Commission standards when obligated to abide by both?" dans: Journal of AHIMA / American Health Information Management Association, Vol. 72, Issue 7, pp. 87-8, (2005) (PubMed).
: "Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea." dans: Experimental eye research, Vol. 72, Issue 1, pp. 87-92, (2001) (PubMed).
: "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 14, Issue 7, pp. 973-81, (2000) (PubMed).
: "Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons." dans: Genes & development, Vol. 14, Issue 17, pp. 2216-28, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à DDR1
Discoidin domain receptor (Ddr), discoidin domain receptor family, member 1 (Ddr1), discoidin domain receptor tyrosine kinase 1 (DDR1), discoidin domain receptor tyrosine kinase 1 (Ddr1), 6030432F18, AI323681, Cak, CAK, CD167, CD167a, CG9488, CG9490, CG11573, CG13984, CG13985, CG33531, CT33540, DDR, Dmel\\CG33531, Dmel_CG13984, Drd1, EDDR1, HGK2, MCK10, Nep, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKEProtein level used designations for DDR1
- CG33531-PA
- CG33531-PB
- Ddr-PA
- Ddr-PB
- discoidin domain receptor
- CD167 antigen-like family member A
- cell adhesion kinase
- discoidin receptor tyrosine kinase
- epithelial discoidin domain receptor 1
- epithelial discoidin domain-containing receptor 1
- protein-tyrosine kinase MPK-6
- tyrosine kinase DDR
- tyrosine-protein kinase CAK
- PTK3A protein tyrosine kinase 3A
- mammary carcinoma kinase 10
- neuroepithelial tyrosine kinase
- neurotrophic tyrosine kinase, receptor, type 4
- protein-tyrosine kinase RTK-6
- discoidin domain receptor family, member 1
- neurotrophic tyrosine kinase receptor type 4
- protein-tyrosine kinase 3
- protein-tyrosine kinase PTK-3
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