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DEFA5 Produits

(Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Catégories

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Jul 2008].

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Catégories DEFA5 en vedette

DEFA5 Anticorps

High quality antibodies with extensive validation data.

DEFA5 Kits ELISA

Reliable ELISA kits for a wide range of species.

DEFA5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DEFA5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (2)
N° du produit ABIN514948
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (fro), IA
Validations
  • (3)
N° du produit ABIN2192079
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
N° du produit ABIN1175204
Quantité 100 μL
Fiche technique Fiche technique

DEFA5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955306
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955307
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6999455
Quantité 96 tests
Fiche technique Fiche technique

DEFA5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351413
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412587
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412590
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DEFA5

Jabari, Schrödl, Kaser-Eichberger, Kofler, Brehmer: "Alarin in different human intestinal epithelial cell types." dans: Histochemistry and cell biology, (2019) (PubMed).

Cerrillo, Moret, Iborra, Ramos, Busó, Tortosa, Sáez-González, Nos, Beltrán: "Alpha-defensins (α-Defs) in Crohn's disease: decrease of ileal α-Def 5 via permanent methylation and increase in plasma α-Def 1-3 concentrations offering biomarker utility." dans: Clinical and experimental immunology, (2018) (PubMed).

Liu, Naito, Liu, VanDussen, Haritunians, Li, Endo, Kawai, Nagasaki, Kinouchi, McGovern, Shimosegawa, Kakuta, Stappenbeck: "LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients." dans: JCI insight, Vol. 2, Issue 6, pp. e91917, (2017) (PubMed).

Múnera, Sundaram, Rankin, Hill, Watson, Mahe, Vallance, Shroyer, Sinagoga, Zarzoso-Lacoste, Hudson, Howell, Chatuvedi, Spence, Shannon, Zorn, Helmrath, Wells: "Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling." dans: Cell stem cell, Vol. 21, Issue 1, pp. 51-64.e6, (2017) (PubMed).

Vragniau, Hübner, Beidler, Gil, Saydaminova, Lu, Yumul, Wang, Richter, Sova, Drescher, Fender, Lieber: "Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy." dans: Journal of virology, Vol. 91, Issue 6, (2017) (PubMed).

Liu, Gurram, Baldridge, Head, Lam, Luo, Cao, Simpson, Hayward, Holtz, Bousounis, Noe, Lerner, Cabrera, Biank, Stephens, Huttenhower, McGovern, Xavier, Stappenbeck, Salzman: "Paneth cell defects in Crohn's disease patients promote dysbiosis." dans: JCI insight, Vol. 1, Issue 8, pp. e86907, (2016) (PubMed).

Alam, Rashid, Kabir, Raqib, Ahmad: "On birth single dose live attenuated OPV and BCG vaccination induces gut cathelicidin LL37 responses at 6 week of age: a natural experiment." dans: Vaccine, Vol. 33, Issue 1, pp. 18-21, (2014) (PubMed).

Jung, Kim, Yeom, Yoo, Shin, Yoo, Kang, Lee: "Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer." dans: Journal of gastroenterology, Vol. 47, Issue 1, pp. 37-48, (2012) (PubMed).

Kim, Kang, Lee, Jung, Lee, Yu, Kim, Lee: "Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes." dans: Journal of proteomics, Vol. 75, Issue 10, pp. 2983-97, (2012) (PubMed).

Bukurova, Nikitina, Khankin, Krasnov, Lisitsin, Karpov, Beresten: "[Identification of protein markers for serum diagnosis of cancer based on microRNA expression profiling]." dans: Molekuliarnaia biologiia, Vol. 45, Issue 2, pp. 376-81, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à DEFA5

defensin alpha 5 (DEFA5), defensin, alpha, 5 (Defa5), defensin, alpha 5, Paneth cell-specific (DEFA5), defensin alpha 5 (Defa5), alpha-defensin 1A (MNP1A), DEF5, Defa, DEFA1, DEFA5, Defa29, Defcr5, Defcr29, HD-5

Protein level used designations for DEFA5

  • HD5(20-94)
  • defensin 5
  • defensin, alpha 5, preproprotein
  • defensin-5
  • alpha-defensin 5
  • defensin, alpha, 29
  • defensin-related cryptdin-5
  • alpha-defensin 5, Paneth cell-specific
  • defensin, alpha 1
  • Paneth cell-specific alpha-defensin 5
  • defensin NP-2
  • neutrophil antibiotic peptide NP-1
  • neutrophil antibiotic peptide NP-2
  • neutrophil defensin 1
  • neutrophil defensin 2
  • ratNP-1
  • ratNP-2
  • Neutrophil defensin 1
  • Neutrophil defensin 3
  • RMAD-1
  • RMAD-3
  • RMAD-8
  • neutrophil defensin 8
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