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DEK Produits

(DEK Oncogene (DEK))
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories DEK en vedette

DEK Anticorps

High quality antibodies with extensive validation data.

DEK Kits ELISA

Reliable ELISA kits for a wide range of species.

DEK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DEK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
N° du produit ABIN653133
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
N° du produit ABIN7266724
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
  • (4)
N° du produit ABIN968269
Quantité 50 μg
Fiche technique Fiche technique

DEK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6974951
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5591964
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1150831
Quantité 96 tests
Fiche technique Fiche technique

DEK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2719372
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Cat, Human, Monkey, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2746433
Quantité 5 applications
Fiche technique Fiche technique

Dernières publications sur nos produits DEK

Wise-Draper, Sendilnathan, Palackdharry, Pease, Qualtieri, Butler, Sadraei, Morris, Patil, Wilson, Mark, Casper, Takiar, Lane, Privette Vinnedge: "Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma." dans: Translational oncology, Vol. 11, Issue 1, pp. 168-174, (2018) (PubMed).

Matrka, Cimperman, Haas, Guasch, Ehrman, Waclaw, Komurov, Lane, Wikenheiser-Brokamp, Wells: "Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence." dans: PLoS genetics, Vol. 14, Issue 3, pp. e1007227, (2018) (PubMed).

Yang, Wu, Geng, Liu, Yang, Chen, Ding, He, Wang, Xie: "Roles of DEK in the endometrium of mice in early pregnancy." dans: Gene, Vol. 642, pp. 261-267, (2017) (PubMed).

Wang, Eckert, Zomorrodi, Xin, Pan, Shearer, Weisz, Maranus, Clawson: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).

Privette Vinnedge, McClaine, Wagh, Wikenheiser-Brokamp, Waltz, Wells: "The human DEK oncogene stimulates ?-catenin signaling, invasion and mammosphere formation in breast cancer." dans: Oncogene, Vol. 30, Issue 24, pp. 2741-52, (2011) (PubMed).

Datta, Adelson, Mogilevkin, Mordechai, Sidi, Trama: "Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer." dans: BMC cancer, Vol. 11, pp. 234, (2011) (PubMed).

Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." dans: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

Clawson, Bui, Xin, Wang, Pan: "Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins." dans: Journal of cellular biochemistry, Vol. 105, Issue 1, pp. 81-8, (2008) (PubMed).

Fu, Grosveld, Markovitz: "DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 5, pp. 1811-5, (1997) (PubMed).

Fu, Markovitz: "Purification of the pets factor. A nuclear protein that binds to the inducible TG-rich element of the human immunodeficiency virus type 2 enhancer." dans: The Journal of biological chemistry, Vol. 271, Issue 32, pp. 19599-605, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à DEK

DEK proto-oncogene (DEK), DEK proto-oncogene (Dek), DEK proto-oncogene L homeolog (dek.L), DEK oncogene (DNA binding) (Dek), DEK oncogene (LOC398543), 1810019E15Rik, D6S231E, D13H6S231E, DEK

Protein level used designations for DEK

  • DEK oncogene (DNA binding)
  • protein DEK
  • DEK oncogene
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