DERL1 Produits
(Der1-Like Domain Family, Member 1 (DERL1))
Catégories
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].
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Catégories DERL1 en vedette
DERL1 Anticorps
High quality antibodies with extensive validation data.
DERL1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DERL1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN652693
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (2)
N° du produit
ABIN1386486
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, IHC (p), FACS
Validations
- (2)
N° du produit
ABIN1978394
Quantité
200 μL
Fiche technique
Fiche technique
DERL1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351465
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351467
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DERL1
: "Rab2A is a pivotal switch protein that promotes either secretion or ER-associated degradation of (pro)insulin in insulin-secreting cells." dans: Scientific reports, Vol. 4, pp. 6952, (2014) (PubMed).: "HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation." dans: The Journal of biological chemistry, Vol. 282, Issue 38, pp. 28285-95, (2007) (PubMed).
: "Cell biology: a channel for protein waste." dans: Nature, Vol. 429, Issue 6994, pp. 817-8, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à DERL1
Derlin-1 (Der-1), derlin-1 (EDI_023440), derlin-1.1 (PTRG_01331), hypothetical protein (derl1), Der1-like domain family, member 1 (DERL1), derlin 1 (derl1), derlin 1 L homeolog (derl1.L), derlin 1 (DERL1), Der1-like domain family, member 1 (Derl1), derlin 1 (Derl1), DERLIN-1 (DER1), 1110021N07Rik, AI195141, AW551338, CG10908, DDBDRAFT_0188135, DDBDRAFT_0266772, DDB_0188135, DDB_0266772, DER-1, DER1, Derlin-1, derlin-1, DERLIN-1, Dmel\\CG10908, F17A13.150, F17A13_150, MGC84200, RGD1311835, wu:fb09d07, wu:fb94d05, wu:fj92g12, zgc:55637Protein level used designations for DERL1
- CG10908-PA
- CG10908-PB
- Der-1-PA
- Der-1-PB
- Dm Derlin-1
- derlin-1
- derlin-1.1
- Der1-like domain family, member 1
- Der1-like protein 1
- degradation in endoplasmic reticulum protein 1
- der1-like protein 1
- DERtrin-1
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