DKK2 Produits
(Dickkopf 2 Homolog (DKK2))
Catégories
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008].
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Catégories DKK2 en vedette
DKK2 Anticorps
High quality antibodies with extensive validation data.
DKK2 Kits ELISA
Reliable ELISA kits for a wide range of species.
DKK2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DKK2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7149882
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN6749760
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
N° du produit
ABIN7433045
Quantité
100 μL
Fiche technique
Fiche technique
DKK2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6955381
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966354
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966352
Quantité
96 tests
Fiche technique
Fiche technique
DKK2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122658
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN6964354
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7539309
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DKK2
: "Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1." dans: Nature cell biology, Vol. 19, Issue 10, pp. 1274-1285, (2017) (PubMed).: "Rheumatoid arthritis bone fragility is associated with upregulation of IL17 and DKK1 gene expression." dans: Clinical reviews in allergy & immunology, Vol. 47, Issue 1, pp. 38-45, (2014) (PubMed).
: "DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma." dans: Cancer research, Vol. 73, Issue 2, pp. 967-77, (2013) (PubMed).
: "Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells." dans: British journal of cancer, Vol. 108, Issue 10, pp. 2070-8, (2013) (PubMed).
: "Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma." dans: Carcinogenesis, Vol. 33, Issue 12, pp. 2334-43, (2012) (PubMed).
: "Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development." dans: International journal of oncology, Vol. 37, Issue 6, pp. 1495-501, (2011) (PubMed).
: "Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 18, pp. 5678-87, (2009) (PubMed).
: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." dans: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
: "Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins." dans: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6100-10, (2002) (PubMed).
: "Functional and structural diversity of the human Dickkopf gene family." dans: Gene, Vol. 238, Issue 2, pp. 301-13, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à DKK2
dickkopf WNT signaling pathway inhibitor 2 (DKK2), dickkopf WNT signaling pathway inhibitor 2 (Dkk2), dickkopf WNT signaling pathway inhibitor 2 (dkk2), DKK-2, Dkk4, zgc:171574Protein level used designations for DKK2
- dickkopf 2 homolog
- dickkopf homolog 2
- dickkopf related protein-2
- dickkopf-2
- dickkopf-related protein 2
- hDkk-2
- dickkopf 2
- dickkopf homolog 1
- dkk-2
- mDkk-2
- dickkopf homolog 4
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