DLAT Produits
(Dihydrolipoyl Transacetylase (DLAT))
Catégories
This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009].
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Catégories DLAT en vedette
DLAT Anticorps
High quality antibodies with extensive validation data.
DLAT Kits ELISA
Reliable ELISA kits for a wide range of species.
DLAT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DLAT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7432412
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN7257932
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN7266768
Quantité
100 μL
Fiche technique
Fiche technique
DLAT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966368
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955387
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1114634
Quantité
96 tests
Fiche technique
Fiche technique
DLAT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122666
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351656
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7403039
Quantité
100 μg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à DLAT
midline uncoordinated (muc), dihydrolipoamide S-acetyltransferase L homeolog (dlat.L), dihydrolipoamide S-acetyltransferase (DLAT), dihydrolipoamide S-acetyltransferase (Dlat), dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (dlat), dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (Dlat), 6332404G05Rik, anon-WO0118547.121, DLAT, DLTA, Dmel\\CG5261, EP(2)0816, EP816, PDC-E2, PDCE2, wu:fc14f10, wu:fc21f08, wu:fc86g11, wu:fj57d06Protein level used designations for DLAT
- CG5261-PA
- CG5261-PB
- CG5261-PC
- CG5261-PD
- CG5261-PE
- CG5261-PF
- Dihydrolipoyllysine-residue acetyltransferase
- dihydrolipoamide acetyltransferase
- dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
- 70 kDa mitochondrial autoantigen of primary biliary cirrhosis
- E2 component of pyruvate dehydrogenase complex
- M2 antigen complex 70 kDa subunit
- PBC
- dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial
- dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- pyruvate dehydrogenase complex component E2
- dihydrolipoyllysine-residue acetyltransferase
- E2
- PDC-E2
- PDCE2
- fc86g11
- fj57d06
- no optokinetic nystagmus a
- no optokinetic response b
- noa
- nrb
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