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DMPK Produits

(Dystrophia Myotonica-Protein Kinase (DMPK))

Catégories

The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

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Catégories DMPK en vedette

DMPK Anticorps

High quality antibodies with extensive validation data.

DMPK Kits ELISA

Reliable ELISA kits for a wide range of species.

DMPK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DMPK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (6)
N° du produit ABIN7073790
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (5)
N° du produit ABIN950119
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
N° du produit ABIN515032
Quantité 100 μg
Fiche technique Fiche technique

DMPK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648192
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1143793
Quantité 96 tests
Fiche technique Fiche technique

DMPK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351723
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5508895
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7423321
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DMPK

Ramasamy, Ren, Mench, Regan: "Impact of initial biofilm growth on the anode impedance of microbial fuel cells." dans: Biotechnology and bioengineering, Vol. 101, Issue 1, pp. 101-8, (2008) (PubMed).

Jin, Shimizu, Balasubramanyam, Epstein: "Myotonic dystrophy protein kinase (DMPK) induces actin cytoskeletal reorganization and apoptotic-like blebbing in lens cells." dans: Cell motility and the cytoskeleton, Vol. 45, Issue 2, pp. 133-48, (2000) (PubMed).

Pham, Man, Lam, Morris: "Localization of myotonic dystrophy protein kinase in human and rabbit tissues using a new panel of monoclonal antibodies." dans: Human molecular genetics, Vol. 7, Issue 12, pp. 1957-65, (1998) (PubMed).

Mahadevan, Amemiya, Jansen, Sabourin, Baird, Neville, Wormskamp, Segers, Batzer, Lamerdin: "Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene." dans: Human molecular genetics, Vol. 2, Issue 3, pp. 299-304, (1993) (PubMed).

Synonymes et noms alternatifs relatifs à DMPK

DM1 protein kinase (DMPK), dystrophia myotonica-protein kinase (Dmpk), DM1 protein kinase (Dmpk), DM, DM1, DM1PK, Dm15, DMK, DMPK, MDPK, MT-PK

Protein level used designations for DMPK

  • dystrophia myotonica-protein kinase
  • myotonic dystrophy protein kinase
  • myotonin-protein kinase-like
  • DM protein kinase
  • DM-kinase
  • DM1 protein kinase
  • myotonic dystrophy associated protein kinase
  • myotonin protein kinase A
  • myotonin-protein kinase
  • thymopoietin homolog
  • dystrophia myotonica kinase, B15
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