DNASE1 Produits
(Deoxyribonuclease I (DNASE1))
Catégories
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
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Catégories DNASE1 en vedette
DNASE1 Anticorps
High quality antibodies with extensive validation data.
DNASE1 Kits ELISA
Reliable ELISA kits for a wide range of species.
DNASE1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DNASE1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7433180
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ICC, IF, IHC (p)
Validations
- (4)
N° du produit
ABIN2856669
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (4)
N° du produit
ABIN3016215
Quantité
100 μL
Fiche technique
Fiche technique
DNASE1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
N° du produit
ABIN6574255
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966327
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966325
Quantité
96 tests
Fiche technique
Fiche technique
DNASE1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122635
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351834
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505085
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DNASE1
: "Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes." dans: Biochimie, Vol. 174, pp. 34-43, (2021) (PubMed).: "Biomarkers of neutrophil extracellular traps (NETs) and nitric oxide-(NO)-dependent oxidative stress in women who miscarried." dans: Scientific reports, Vol. 10, Issue 1, pp. 13088, (2020) (PubMed).
: "Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure." dans: Journal of cardiac failure, Vol. 22, Issue 10, pp. 823-8, (2016) (PubMed).
: "Ocular surface extracellular DNA and nuclease activity imbalance: a new paradigm for inflammation in dry eye disease." dans: Investigative ophthalmology & visual science, Vol. 53, Issue 13, pp. 8253-63, (2012) (PubMed).
: "Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c." dans: The Journal of biological chemistry, Vol. 266, Issue 4, pp. 2134-42, (1991) (PubMed).
: "A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells." dans: European journal of immunology, Vol. 21, Issue 1, pp. 143-51, (1991) (PubMed).
Synonymes et noms alternatifs relatifs à DNASE1
DNase I (endA), DNase I (LOC397802), deoxyribonuclease 1 (DNASE1), deoxyribonuclease I (Dnase1), deoxyribonuclease 1 (Dnase1), deoxyribonuclease I L homeolog (dnase1.L), deoxyribonuclease I (dnase1), deoxyribonuclease I (CpipJ_CPIJ011184), deoxyribonuclease I (CpipJ_CPIJ011185), deoxyribonuclease I (CpipJ_CPIJ011186), deoxyribonuclease I (CpipJ_CPIJ011187), deoxyribonuclease I (CpipJ_CPIJ011190), deoxyribonuclease I (CpipJ_CPIJ017803), Deoxyribonuclease I (Desal_1409), deoxyribonuclease I (MPET_RS05255), deoxyribonuclease I (METEV_RS02275), deoxyribonuclease I (Plabr_0631), AI788650, dnase1-A, DNaseI, DNL1, Dnl1, DRNI, LOC397802, zgc:92440Protein level used designations for DNASE1
- DNase I
- DNase I, lysosomal
- Dornase alfa
- deoxyribonuclease-1
- human urine deoxyribonuclease I
- deoxyribonuclease I
- Deoxyribonuclease I
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