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DNASE1 Produits

(Deoxyribonuclease I (DNASE1))

Catégories

This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

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Catégories DNASE1 en vedette

DNASE1 Anticorps

High quality antibodies with extensive validation data.

DNASE1 Kits ELISA

Reliable ELISA kits for a wide range of species.

DNASE1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DNASE1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7433180
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ICC, IF, IHC (p)
Validations
  • (4)
N° du produit ABIN2856669
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
N° du produit ABIN3016215
Quantité 100 μL
Fiche technique Fiche technique

DNASE1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
N° du produit ABIN6574255
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966327
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966325
Quantité 96 tests
Fiche technique Fiche technique

DNASE1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122635
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351834
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505085
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DNASE1

Zhdanov, Plyasova, Pokrovsky, Pokrovskaya, Alexandrova, Gladilina, Sokolov: "Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes." dans: Biochimie, Vol. 174, pp. 34-43, (2021) (PubMed).

Omeljaniuk, Jabłońska, Garley, Pryczynicz, Ratajczak-Wrona, Socha, Borawska, Charkiewicz: "Biomarkers of neutrophil extracellular traps (NETs) and nitric oxide-(NO)-dependent oxidative stress in women who miscarried." dans: Scientific reports, Vol. 10, Issue 1, pp. 13088, (2020) (PubMed).

Dhondup, Ueland, Dahl, Askevold, Sandanger, Fiane, Ohm, Sjaastad, Finsen, Wæhre, Gullestad, Aukrust, Yndestad, Vinge: "Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure." dans: Journal of cardiac failure, Vol. 22, Issue 10, pp. 823-8, (2016) (PubMed).

Sonawane, Khanolkar, Namavari, Chaudhary, Gandhi, Tibrewal, Jassim, Shaheen, Hallak, Horner, Newcomb, Sarkar, Jain: "Ocular surface extracellular DNA and nuclease activity imbalance: a new paradigm for inflammation in dry eye disease." dans: Investigative ophthalmology & visual science, Vol. 53, Issue 13, pp. 8253-63, (2012) (PubMed).

Goshorn, Retzel, Jemmerson: "Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c." dans: The Journal of biological chemistry, Vol. 266, Issue 4, pp. 2134-42, (1991) (PubMed).

Jemmerson, Johnson, Burrell, Taylor, Jenkins: "A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells." dans: European journal of immunology, Vol. 21, Issue 1, pp. 143-51, (1991) (PubMed).

Synonymes et noms alternatifs relatifs à DNASE1

DNase I (endA), DNase I (LOC397802), deoxyribonuclease 1 (DNASE1), deoxyribonuclease I (Dnase1), deoxyribonuclease 1 (Dnase1), deoxyribonuclease I L homeolog (dnase1.L), deoxyribonuclease I (dnase1), deoxyribonuclease I (CpipJ_CPIJ011184), deoxyribonuclease I (CpipJ_CPIJ011185), deoxyribonuclease I (CpipJ_CPIJ011186), deoxyribonuclease I (CpipJ_CPIJ011187), deoxyribonuclease I (CpipJ_CPIJ011190), deoxyribonuclease I (CpipJ_CPIJ017803), Deoxyribonuclease I (Desal_1409), deoxyribonuclease I (MPET_RS05255), deoxyribonuclease I (METEV_RS02275), deoxyribonuclease I (Plabr_0631), AI788650, dnase1-A, DNaseI, DNL1, Dnl1, DRNI, LOC397802, zgc:92440

Protein level used designations for DNASE1

  • DNase I
  • DNase I, lysosomal
  • Dornase alfa
  • deoxyribonuclease-1
  • human urine deoxyribonuclease I
  • deoxyribonuclease I
  • Deoxyribonuclease I
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