DNMT3A Produits
(DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
Catégories
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories DNMT3A en vedette
DNMT3A Anticorps
High quality antibodies with extensive validation data.
DNMT3A Kits ELISA
Reliable ELISA kits for a wide range of species.
DNMT3A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DNMT3A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (10)
- (5)
N° du produit
ABIN387881
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (3)
- (7)
N° du produit
ABIN3022834
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
- (4)
N° du produit
ABIN669336
Quantité
100 μL
Fiche technique
Fiche technique
DNMT3A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962647
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955416
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1884515
Quantité
96 tests
Fiche technique
Fiche technique
DNMT3A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (2)
N° du produit
ABIN2719617
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122679
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351868
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DNMT3A
: "Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency." dans: Cell stem cell, Vol. 24, Issue 1, pp. 123-137.e8, (2019) (PubMed).: "Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions. ..." dans: Nature genetics, Vol. 51, Issue 1, pp. 96-105, (2019) (PubMed).
: "Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally." dans: Diabetes, Vol. 68, Issue 2, pp. 337-348, (2019) (PubMed).
: "The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells." dans: Molecular carcinogenesis, (2018) (PubMed).
: "Identification of dynamic undifferentiated cell states within the male germline." dans: Nature communications, Vol. 9, Issue 1, pp. 2819, (2018) (PubMed).
: "Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle." dans: Reproduction, fertility, and development, Vol. 29, Issue 9, pp. 1729-1738, (2018) (PubMed).
: "DNA Demethylation by DNMT3A and DNMT3B in vitro and of Methylated Episomal DNA in Transiently Transfected Cells." dans: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 11, pp. 1048-1061, (2018) (PubMed).
: "MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6262-6274, (2018) (PubMed).
: "Intragenic DNA methylation prevents spurious transcription initiation." dans: Nature, Vol. 543, Issue 7643, pp. 72-77, (2017) (PubMed).
: "Epigenetic determinants of space radiation-induced cognitive dysfunction." dans: Scientific reports, Vol. 7, pp. 42885, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à DNMT3A
DNA methyltransferase 3 alpha (DNMT3A), DNA methyltransferase 3A (Dnmt3a), DNA methyltransferase 3 alpha (Dnmt3a), DNA methyltransferase 3 alpha (dnmt3a), DNA (cytosine-5-)-methyltransferase 3 alpha b (dnmt3ab), DNMT3A, dnmt3a1, DNMT3A2, dnmt6, M.HsaIIIA, MmuIIIAProtein level used designations for DNMT3A
- DNA (cytosine-5)-methyltransferase 3A
- DNA cytosine methyltransferase 3 alpha
- DNA (cytosine-5-)-methyltransferase 3 alpha
- DNA MTase HsaIIIA
- DNA cytosine methyltransferase 3A2
- DNA methyltransferase 3A
- DNA methyl transferase alpha
- DNA-methyltransferase 3a
- DNA MTase MmuIIIA
- DNA methyltransferase MmuIIIA
- LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3A
- DNA (cytosine-5-)-methyltransferase 6
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