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DNMT3B Produits

(DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011].

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Catégories DNMT3B en vedette

DNMT3B Anticorps

High quality antibodies with extensive validation data.

DNMT3B Kits ELISA

Reliable ELISA kits for a wide range of species.

DNMT3B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DNMT3B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (6)
N° du produit ABIN5542518
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (6)
N° du produit ABIN5542517
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (12)
  • (3)
N° du produit ABIN387884
Quantité 400 μL
Fiche technique Fiche technique

DNMT3B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955417
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955418
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5690866
Quantité 96 tests
Fiche technique Fiche technique

DNMT3B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1777739
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
N° du produit ABIN2719618
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409305
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DNMT3B

Arab, Karaulanov, Musheev, Trnka, Schäfer, Grummt, Niehrs: "GADD45A binds R-loops and recruits TET1 to CpG island promoters." dans: Nature genetics, Vol. 51, Issue 2, pp. 217-223, (2019) (PubMed).

Ponnaluri, Estève, Ruse, Pradhan: "S-adenosylhomocysteine Hydrolase Participates in DNA Methylation Inheritance." dans: Journal of molecular biology, Vol. 430, Issue 14, pp. 2051-2065, (2018) (PubMed).

Neri, Rapelli, Krepelova, Incarnato, Parlato, Basile, Maldotti, Anselmi, Oliviero: "Intragenic DNA methylation prevents spurious transcription initiation." dans: Nature, Vol. 543, Issue 7643, pp. 72-77, (2017) (PubMed).

Kumar, Bryan, Esebua, Amos-Landgraf, May: "Testis specific Y-like 5: gene expression, methylation and implications for drug sensitivity in prostate carcinoma." dans: BMC cancer, Vol. 17, Issue 1, pp. 158, (2017) (PubMed).

Mahadevan, Sathappan, Utama, Lorenzo, Kaskar, Van den Veyver: "Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming." dans: Scientific reports, Vol. 7, pp. 44667, (2017) (PubMed).

Liu, Sun, Fong, Yang, Zhang, Yin, Jiang, Liu, Ju, Huang, Bai, Gong, Yan, Zhang, Shao: "An association between overexpression of DNA methyltransferase 3B4 and clear cell renal cell carcinoma." dans: Oncotarget, Vol. 8, Issue 12, pp. 19712-19722, (2017) (PubMed).

Hong, Su, Zhang, Yang, Guo, Li, Kong: "Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway." dans: The AAPS journal, Vol. 18, Issue 3, pp. 659-69, (2016) (PubMed).

Daniel, Alves, Vieira, Biz, Daniel, Modolo: "Immunohistochemical expression of DNA methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas." dans: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 45, Issue 10, pp. 774-779, (2016) (PubMed).

Li, Ma, Dasgupta, Halavi, Hartman, Xiao, Zhang: "Inhibition of DNA Methylation in the Developing Rat Brain Disrupts Sexually Dimorphic Neurobehavioral Phenotypes in Adulthood." dans: Molecular neurobiology, (2016) (PubMed).

Williams, Fernandez-Alonso, Wang, Toth, Gray, Findlay: "Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity." dans: Cell reports, Vol. 16, Issue 7, pp. 1820-8, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à DNMT3B

DNA methyltransferase 3 beta (DNMT3B), DNA methyltransferase 3 beta (Dnmt3b), DNA methyltransferase 3 beta (dnmt3b), DNA methyltransferase 3B (Dnmt3b), DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a (dnmt3ba), cb91, DNMT3B, dnmt3bl, dnmt7, ICF, ICF1, LOC100218113, M.HsaIIIB, MmuIIIB, sb:cb91, wu:fb16h07

Protein level used designations for DNMT3B

  • DNA cytosine-5 methyltransferase 3 beta
  • DNA (cytosine-5)-methyltransferase 3B
  • DNA methyltransferase HsaIIIB
  • DNA (cytosine-5-)-methyltransferase 3 beta
  • DNA MTase HsaIIIB
  • DNA methyltransferase 3B
  • DNA (cytosine-5)-methyltransferase 3B-like
  • DNA MTase MmuIIIB
  • DNA methyltransferase MmuIIIB
  • DNA (cytosine-5-)-methyltransferase 3 beta, like
  • DNA (cytosine-5-)-methyltransferase 7
  • fb16h07
  • LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B
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