DNMT3L Produits
(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
Catégories
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
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Catégories DNMT3L en vedette
DNMT3L Anticorps
High quality antibodies with extensive validation data.
DNMT3L Kits ELISA
Reliable ELISA kits for a wide range of species.
DNMT3L Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DNMT3L recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
N° du produit
ABIN5542515
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP
Validations
- (5)
N° du produit
ABIN526180
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN7260352
Quantité
200 μL
Fiche technique
Fiche technique
DNMT3L recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960699
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN4993275
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative
Validations
N° du produit
ABIN2947075
Quantité
96 tests
Fiche technique
Fiche technique
DNMT3L recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122681
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122680
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351873
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DNMT3L
: "Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands." dans: BMC genomics, Vol. 16, pp. 517, (2016) (PubMed).: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." dans: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).
: "DNA methyl transferases are differentially expressed in the human anterior eye segment." dans: Acta ophthalmologica, Vol. 92, Issue 5, pp. e366-71, (2014) (PubMed).
: "An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism." dans: PLoS ONE, Vol. 8, Issue 4, pp. e61758, (2013) (PubMed).
: "Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation." dans: The EMBO journal, Vol. 26, Issue 8, pp. 2052-60, (2007) (PubMed).
: "Dnmt3L is a transcriptional repressor that recruits histone deacetylase." dans: Nucleic acids research, Vol. 30, Issue 17, pp. 3831-8, (2002) (PubMed).
: "The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16916-21, (2002) (PubMed).
: "Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths." dans: Molecular reproduction and development, Vol. 63, Issue 3, pp. 269-72, (2002) (PubMed).
: "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. ..." dans: Nature, Vol. 420, Issue 6915, pp. 563-73, (2002) (PubMed).
: "Isolation and initial characterization of the mouse Dnmt3l gene." dans: Cytogenetics and cell genetics, Vol. 92, Issue 1-2, pp. 122-6, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à DNMT3L
DNA methyltransferase 3 like (DNMT3L), DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l), DNA methyltransferase 3 like (Dnmt3l), D6Ertd14e, DNMT3L, ecat7Protein level used designations for DNMT3L
- DNA (cytosine-5-)-methyltransferase 3-like
- cytosine-5-methyltransferase 3-like protein
- DNA (cytosine-5)-methyltransferase 3-like
- human cytosine-5-methyltransferase 3-like protein
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