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DNMT3L Produits

(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Catégories

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].

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Catégories DNMT3L en vedette

DNMT3L Anticorps

High quality antibodies with extensive validation data.

DNMT3L Kits ELISA

Reliable ELISA kits for a wide range of species.

DNMT3L Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DNMT3L recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (5)
N° du produit ABIN5542515
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
N° du produit ABIN526180
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7260352
Quantité 200 μL
Fiche technique Fiche technique

DNMT3L recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960699
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN4993275
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative
Validations
N° du produit ABIN2947075
Quantité 96 tests
Fiche technique Fiche technique

DNMT3L recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122681
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122680
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351873
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DNMT3L

Das, Chai, Kim, Lee, Park, Jung, Chai: "Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands." dans: BMC genomics, Vol. 16, pp. 517, (2016) (PubMed).

Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." dans: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).

Bonnin, Belville, Chiambaretta, Sapin, Blanchon: "DNA methyl transferases are differentially expressed in the human anterior eye segment." dans: Acta ophthalmologica, Vol. 92, Issue 5, pp. e366-71, (2014) (PubMed).

Ajj, Chesnel, Pinel, Plenat, Flament, Dumond: "An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism." dans: PLoS ONE, Vol. 8, Issue 4, pp. e61758, (2013) (PubMed).

Yu, Thieu, Kaplan: "Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation." dans: The EMBO journal, Vol. 26, Issue 8, pp. 2052-60, (2007) (PubMed).

Deplus, Brenner, Burgers, Putmans, Kouzarides, de Launoit, Fuks: "Dnmt3L is a transcriptional repressor that recruits histone deacetylase." dans: Nucleic acids research, Vol. 30, Issue 17, pp. 3831-8, (2002) (PubMed).

Chedin, Lieber, Hsieh: "The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16916-21, (2002) (PubMed).

Kierszenbaum: "Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths." dans: Molecular reproduction and development, Vol. 63, Issue 3, pp. 269-72, (2002) (PubMed).

Okazaki, Furuno, Kasukawa, Adachi, Bono, Kondo, Nikaido, Osato, Saito, Suzuki, Yamanaka, Kiyosawa, Yagi, Tomaru, Hasegawa, Nogami, Schönbach, Gojobori, Baldarelli, Hill, Bult, Hume, Quackenbush et al.: "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. ..." dans: Nature, Vol. 420, Issue 6915, pp. 563-73, (2002) (PubMed).

Aapola, Lyle, Krohn, Antonarakis, Peterson: "Isolation and initial characterization of the mouse Dnmt3l gene." dans: Cytogenetics and cell genetics, Vol. 92, Issue 1-2, pp. 122-6, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à DNMT3L

DNA methyltransferase 3 like (DNMT3L), DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l), DNA methyltransferase 3 like (Dnmt3l), D6Ertd14e, DNMT3L, ecat7

Protein level used designations for DNMT3L

  • DNA (cytosine-5-)-methyltransferase 3-like
  • cytosine-5-methyltransferase 3-like protein
  • DNA (cytosine-5)-methyltransferase 3-like
  • human cytosine-5-methyltransferase 3-like protein
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