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DROSHA Produits

(Drosha, Ribonuclease Type III (DROSHA))
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM, Mar 2008].

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Catégories DROSHA en vedette

DROSHA Anticorps

High quality antibodies with extensive validation data.

DROSHA Kits ELISA

Reliable ELISA kits for a wide range of species.

DROSHA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DROSHA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
N° du produit ABIN7188005
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN7264363
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (2)
N° du produit ABIN6971610
Quantité 100 μL
Fiche technique Fiche technique

DROSHA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966423
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955459
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5658503
Quantité 96 tests
Fiche technique Fiche technique

DROSHA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318168
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
N° du produit ABIN1691359
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397228
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DROSHA

Veronese, Pepe, Chiacchia, Pagotto, Lanuti, Veschi, Di Marco, DArgenio, Innocenti, Vannata, Autore, Marchisio, Wernicke, Verginelli, Leone, Rassenti, Kipps, Mariani-Costantini, Laurenti, Croce, Visone: "Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia." dans: Leukemia, Vol. 29, Issue 1, pp. 86-95, (2015) (PubMed).

Macias, Cordiner, Gautier, Plass, Cáceres: "DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs." dans: Molecular cell, Vol. 60, Issue 6, pp. 873-85, (2015) (PubMed).

Rupaimoole, Wu, Pradeep, Ivan, Pecot, Gharpure, Nagaraja, Armaiz-Pena, McGuire, Zand, Dalton, Filant, Miller, Lu, Sadaoui, Mangala, Taylor, van den Beucken, Koch, Rodriguez-Aguayo, Huang, Bar-Eli et al.: "Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. ..." dans: Nature communications, Vol. 5, pp. 5202, (2014) (PubMed).

Yamakawa, Okuyama, Ogata, Kanai, Helwak, Takamatsu, Imadome, Takakura, Chanda, Kurosaki, Yamamoto, Ando, Matsui, Inaba, Kotani: "Novel functional small RNAs are selectively loaded onto mammalian Ago1." dans: Nucleic acids research, Vol. 42, Issue 8, pp. 5289-301, (2014) (PubMed).

Teta, Choi, Okegbe, Wong, Tam, Chong, Seykora, Nagy, Littman, Andl, Millar: "Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin." dans: Development (Cambridge, England), Vol. 139, Issue 8, pp. 1405-16, (2012) (PubMed).

Hsieh, Lin, Liu, Chang, Shih, Zhong, Lee, Tan: "WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway." dans: Nucleic acids research, Vol. 39, Issue 10, pp. 4048-62, (2011) (PubMed).

Thomson, Newman, Parker, Morin-Kensicki, Wright, Hammond: "Extensive post-transcriptional regulation of microRNAs and its implications for cancer." dans: Genes & development, Vol. 20, Issue 16, pp. 2202-7, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à DROSHA

ribonuclease type III, nuclear (rnasen), Ribonuclease 3 (Thicy_0885), Ribonuclease 3 (Sinme_0866), ribonuclease 3 (Isova_2087), Ribonuclease 3 (Sphch_0770), drosha ribonuclease III (DROSHA), drosha, ribonuclease type III (DROSHA), drosha, ribonuclease type III (Drosha), drosha ribonuclease III (Drosha), 1110013A17Rik, AI874853, ETOHI2, Etohi2, HSA242976, im:7150667, RANSE3L, RGD1307626, RN3, Rn3, RNASE3L, RNASEN, Rnasen, zgc:158612

Protein level used designations for DROSHA

  • drosha
  • ribonuclease 3
  • Ribonuclease 3
  • RNase III
  • drosha, double-stranded RNA-specific endoribonuclease
  • nuclear RNase III Drosha
  • p241
  • protein Drosha
  • putative protein p241 which interacts with transcription factor Sp1
  • putative ribonuclease III
  • ribonuclease III, nuclear
  • ribonuclease type III, nuclear
  • ethanol induced 2
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