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DUOX2 Produits

(Dual Oxidase 2 (DUOX2))
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008].

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Catégories DUOX2 en vedette

DUOX2 Anticorps

High quality antibodies with extensive validation data.

DUOX2 Kits ELISA

Reliable ELISA kits for a wide range of species.

DUOX2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DUOX2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (2)
N° du produit ABIN655174
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
N° du produit ABIN7150690
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (1)
N° du produit ABIN7434641
Quantité 100 μL
Fiche technique Fiche technique

DUOX2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966425
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955461
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955462
Quantité 96 tests
Fiche technique Fiche technique

DUOX2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7395821
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7395824
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN6122442
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits DUOX2

Dyikanov, Vasiluev, Rysenkova, Aleksandrushkina, Tyurin-Kuzmin, Kulebyakin, Rubtsov, Shmakova, Evseeva, Balatskiy, Semina, Rostovtseva, Makarevich, Karagyaur: "Optimization of CRISPR/Cas9 Technology to Knock Out Genes of Interest in Aneuploid Cell Lines." dans: Tissue engineering. Part C, Methods, Vol. 25, Issue 3, pp. 168-175, (2019) (PubMed).

Jafari, Kim, Park, Li, Jang, Morris, Park, Huang: "CRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa Cells." dans: PLoS ONE, Vol. 12, Issue 1, pp. e0170327, (2017) (PubMed).

Tyurin-Kuzmin, Zhdanovskaya, Sukhova, Sagaradze, Albert, Ageeva, Sharonov, Vorotnikov, Tkachuk: "Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0154157, (2016) (PubMed).

Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." dans: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

Nguyen, Parekh, Chang, Sharma, Carrier: "Contribution of Dual Oxidase 2 (DUOX2) to Hyper-Radiosensitivity in Human Gastric Cancer Cells." dans: Radiation research, Vol. 184, Issue 2, pp. 151-60, (2015) (PubMed).

MacFie, Poulsom, Parker, Warnes, Boitsova, Nijhuis, Suraweera, Poehlmann, Szary, Feakins, Jeffery, Harper, Jubb, Lindsay, Silver: "DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid." dans: Inflammatory bowel diseases, Vol. 20, Issue 3, pp. 514-24, (2014) (PubMed).

Harper, Xu, Eiserich, Chen, Kao, Thai, Setiadi, Wu: "Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium." dans: FEBS letters, Vol. 579, Issue 21, pp. 4911-7, (2005) (PubMed).

Wang, De Deken, Milenkovic, Song, Pirson, Dumont, Miot: "Identification of a novel partner of duox: EFP1, a thioredoxin-related protein." dans: The Journal of biological chemistry, Vol. 280, Issue 4, pp. 3096-103, (2005) (PubMed).

Morand, Chaaraoui, Kaniewski, Dème, Ohayon, Noel-Hudson, Virion, Dupuy: "Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles." dans: Endocrinology, Vol. 144, Issue 4, pp. 1241-8, (2003) (PubMed).

De Deken, Wang, Many, Costagliola, Libert, Vassart, Dumont, Miot: "Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family." dans: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23227-33, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à DUOX2

dual oxidase 2 (DUOX2), dual oxidase 2 (Duox2), A430065P05Rik, LNOX2, NOXEF2, P138-TOX, TDH6, THOX2, Thox2

Protein level used designations for DUOX2

  • dual oxidase 2
  • dual oxidase 2-like
  • NADH/NADPH thyroid oxidase p138-tox
  • NADPH oxidase/peroxidase DUOX2
  • NADPH thyroid oxidase 2
  • dual oxidase-like domains 2
  • flavoprotein NADPH oxidase
  • large NOX 2
  • long NOX 2
  • nicotinamide adenine dinucleotide phosphate oxidase
  • p138 thyroid oxidase
  • thyroid oxidase 2
  • NADH/NADPH thyroid oxidase THOX2
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