DUSP5 Produits
(Dual Specificity Phosphatase 5 (DUSP5))
Catégories
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008].
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Catégories DUSP5 en vedette
DUSP5 Anticorps
High quality antibodies with extensive validation data.
DUSP5 Kits ELISA
Reliable ELISA kits for a wide range of species.
DUSP5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DUSP5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (6)
N° du produit
ABIN560667
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN560666
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
- (1)
- (1)
N° du produit
ABIN1713770
Quantité
100 μL
Fiche technique
Fiche technique
DUSP5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966429
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955467
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955466
Quantité
96 tests
Fiche technique
Fiche technique
DUSP5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352138
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7398719
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7398722
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DUSP5
: "Down-regulation of dual-specificity phosphatase 5 predicts poor prognosis of patients with prostate cancer." dans: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 4186-94, (2015) (PubMed).: "Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats." dans: PLoS ONE, Vol. 9, Issue 11, pp. e112878, (2014) (PubMed).
: "DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis." dans: Oncogene, Vol. 28, Issue 29, pp. 2667-77, (2009) (PubMed).
: "Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5." dans: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1830-45, (2005) (PubMed).
: "Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53." dans: Oncogene, Vol. 22, Issue 36, pp. 5586-91, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à DUSP5
dual specificity phosphatase 5 (DUSP5), dual specificity phosphatase 5 (dusp5), dual specificity phosphatase 5 S homeolog (dusp5.S), dual specificity phosphatase 5 (Dusp5), Cpg21, dusp, DUSP, DUSP5, Gm337, hvh3, HVH3, MGC84792, wu:fc03b11, wu:fc86e02Protein level used designations for DUSP5
- dual specificity protein phosphatase 5-like
- dual specificity phosphatase 5
- dual specificity protein phosphatase 5
- VH1-like phosphatase 3
- dual specificity protein phosphatase hVH3
- serine/threonine specific protein phosphatase
- MAP-kinase phosphatase (cpg21)
- MAP-kinase phosphatase CPG21
- candidate plasticity-related gene 21
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