DUSP8 Produits
(Dual Specificity Phosphatase 8 (DUSP8))
Catégories
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008].
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Catégories DUSP8 en vedette
DUSP8 Anticorps
High quality antibodies with extensive validation data.
DUSP8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DUSP8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7242101
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN7266849
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
N° du produit
ABIN392868
Quantité
400 μL
Fiche technique
Fiche technique
DUSP8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352144
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3079104
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3131391
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits DUSP8
: "Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8." dans: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 5, pp. 1465-77, (2016) (PubMed).: "Identification of a transcriptionally active hVH-5 pseudogene on 10q22.2." dans: Cancer genetics and cytogenetics, Vol. 159, Issue 2, pp. 155-9, (2005) (PubMed).
: "hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase." dans: Journal of neurochemistry, Vol. 65, Issue 4, pp. 1823-33, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à DUSP8
dual specificity phosphatase 8 (DUSP8), dual specificity phosphatase 8 (dusp8), dual specificity phosphatase 8a (dusp8a), dual specificity protein phosphatase 8 (DSP8), dual specificity phosphatase 8 (Dusp8), dual specificity protein phosphatase 8 (LOC615727), 5530400B01Rik, AI593498, C11orf81, DUSP8, HB5, Hb5, HVH-5, HVH8, M3/6, Nttp1, zgc:77593Protein level used designations for DUSP8
- dual specificity phosphatase 8
- dual specificity protein phosphatase 8-like
- dual specificity protein phosphatase 8
- H1 phosphatase, vaccinia virus homolog
- dual specificity protein phosphatase hVH-5
- serine/threonine specific protein phosphatase
- neuronal tyrosine threonine phosphatase 1
- neuronal tyrosine/threonine phosphatase 1
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