Dynactin 1 Produits
(Dynactin 1 (DCTN1))
Catégories
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008].
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Catégories Dynactin 1 en vedette
Dynactin 1 Anticorps
High quality antibodies with extensive validation data.
Dynactin 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Dynactin 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Dynactin 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF, FACS
Validations
- (1)
- (7)
N° du produit
ABIN184834
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, ICC, IHC (p)
Validations
- (4)
N° du produit
ABIN2854663
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Chicken, Dog, Human, Mouse, Rat
Application
WB, IF, IP, IHC (zinc)
Validations
- (5)
- (4)
N° du produit
ABIN967996
Quantité
150 μg
Fiche technique
Fiche technique
Dynactin 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4882617
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6384464
Quantité
96 tests
Fiche technique
Fiche technique
Dynactin 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351220
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3092040
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3131313
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Dynactin 1
: "The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization." dans: Molecular biology of the cell, pp. mbcE18020108, (2018) (PubMed).: "Temporal changes in expression of connexin 43 after load-induced hypertrophy in vitro." dans: American journal of physiology. Heart and circulatory physiology, Vol. 296, Issue 3, pp. H806-14, (2009) (PubMed).
: "Anthrax toxin rafts into cells." dans: The Journal of cell biology, Vol. 160, Issue 3, pp. 295-6, (2003) (PubMed).
: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." dans: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, (2002) (PubMed).
: "NudC associates with Lis1 and the dynein motor at the leading pole of neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 24, pp. RC187, (2001) (PubMed).
: "Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport." dans: The Journal of cell biology, Vol. 153, Issue 7, pp. 1499-509, (2001) (PubMed).
: "Dynactin increases the processivity of the cytoplasmic dynein motor." dans: Nature cell biology, Vol. 2, Issue 1, pp. 20-4, (2000) (PubMed).
: "Localization of the DCTN1 gene encoding p150Glued to human chromosome 2p13 by fluorescence in situ hybridization." dans: Genomics, Vol. 31, Issue 3, pp. 398-9, (1997) (PubMed).
: "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1634-8, (1995) (PubMed).
: "Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued." dans: Nature, Vol. 351, Issue 6327, pp. 579-83, (1991) (PubMed).
Synonymes et noms alternatifs relatifs à Dynactin 1
dynactin subunit 1 (DCTN1), dynactin subunit 1 (Dctn1), dynactin 1 (Dctn1), Dynactin 1, p150 subunit (DCTN1-p150), dynactin subunit 1 L homeolog (dctn1.L), AL022633, CG9206, Chip150, DAP-150, DCTN1, DKFZp469C1813, Dmel\\CG9206, DP-150, Dynactin-1, DYNA_DROME, FCP-D, Glu, Glued, glued, P135, p150, P150, p150/Glued, p150/glued, p150Protein level used designations for Dynactin 1
- 150 kDa dynein-associated polypeptide
- dynactin 1 (p150, glued homolog, Drosophila)
- dynactin subunit 1
- DAP-150
- DP-150
- p150-glued
- dynactin 1
- dynactin subunit 1-like
- dynactin 1, retrograde axonal transport
- CG9206-PA
- Gl-PA
- dynactin
- dynactin P150
- glued
- p150[glued]
- p150glued
- dynactin 1 (p150, glued homolog)
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