DYST Protein (AA 1-195, partial) (His tag)
DYST
Origine: Humain
Hôte: Levure
Recombinant
> 90 %
SDS
1 image
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- Antigène
- DYST (Dystocia (Maternal) (DYST))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-195, partial
- Origine
- Humain
- Source
- Levure
- Purification/Conjugué
- Cette DYST protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSG
- Purification
- SDS-PAGE
- Pureté
- > 90 %
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Antigène
- DYST (Dystocia (Maternal) (DYST))
- Autre désignation
- DYST
- Sujet
- Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh.Isoform 3: plays a structural role in the assbly of hidesmosomes of epithelial cells, anchors keratin-containing intermediate filaments to the inner plaque of hidesmosomes. Required for the regulation of keratinocyte polarity and motility, mediates integrin ITGB4 regulation of RAC1 activity.Isoform 6: required for bundling actin filaments around the nucleus.Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
- Poids moléculaire
- 23.7 kDa
- UniProt
- Q03001
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